Detailed information NTG0893617

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R3H37_RS06910
• Genome accession: NZ_CP136948
• Coordinates: 1403427..1404428 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Spyo01
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1398427..1409428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R3H37_RS06895 (R3H37_06900)	thrS	1398597..1400540 (-)	1944	WP_111715666.1	threonine--tRNA ligase	-
R3H37_RS06900 (R3H37_06905)	-	1400962..1402296 (-)	1335	WP_129284141.1	glycosyltransferase family 4 protein	-
R3H37_RS06905 (R3H37_06910)	-	1402298..1403296 (-)	999	WP_330554617.1	glycosyltransferase family 4 protein	-
R3H37_RS06910 (R3H37_06915)	ccpA	1403427..1404428 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
R3H37_RS06915 (R3H37_06920)	-	1404602..1405687 (+)	1086	WP_063812458.1	aminopeptidase P family protein	-
R3H37_RS06920 (R3H37_06925)	-	1405736..1406401 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
R3H37_RS06925 (R3H37_06930)	-	1406412..1406789 (+)	378	WP_020904973.1	VOC family protein	-
R3H37_RS06930 (R3H37_06935)	-	1406934..1407860 (+)	927	WP_032464862.1	glycosyltransferase family 2 protein	-
R3H37_RS06935 (R3H37_06940)	-	1408071..1408754 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=893617 R3H37_RS06910 WP_002985680.1 1403427..1404428(-) (ccpA) [Streptococcus pyogenes strain Spyo01]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=893617 R3H37_RS06910 WP_002985680.1 1403427..1404428(-) (ccpA) [Streptococcus pyogenes strain Spyo01]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559