Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   RYQ61_RS06365 Genome accession   NZ_CP136799
Coordinates   1228602..1229903 (+) Length   433 a.a.
NCBI ID   WP_048784928.1    Uniprot ID   -
Organism   Streptococcus intermedius strain XH2169     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1223602..1234903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RYQ61_RS06355 (RYQ61_06355) cysK 1226882..1227811 (-) 930 WP_102567781.1 cysteine synthase A -
  RYQ61_RS06360 (RYQ61_06360) - 1227910..1228545 (-) 636 WP_048784930.1 YigZ family protein -
  RYQ61_RS06365 (RYQ61_06365) comFA/cflA 1228602..1229903 (+) 1302 WP_048784928.1 DEAD/DEAH box helicase Machinery gene
  RYQ61_RS06370 (RYQ61_06370) - 1229900..1230565 (+) 666 WP_102567780.1 ComF family protein -
  RYQ61_RS06375 (RYQ61_06375) hpf 1230644..1231186 (+) 543 WP_003073626.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  RYQ61_RS06380 (RYQ61_06380) rsmD 1231385..1231924 (+) 540 WP_048784924.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  RYQ61_RS06385 (RYQ61_06385) coaD 1231914..1232411 (+) 498 WP_003078294.1 pantetheine-phosphate adenylyltransferase -
  RYQ61_RS06390 (RYQ61_06390) sepM 1232392..1233447 (+) 1056 WP_102567779.1 SepM family pheromone-processing serine protease Regulator
  RYQ61_RS06395 (RYQ61_06395) - 1233729..1234292 (+) 564 WP_003073618.1 YutD family protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49285.06 Da        Isoelectric Point: 8.9794

>NTDB_id=892731 RYQ61_RS06365 WP_048784928.1 1228602..1229903(+) (comFA/cflA) [Streptococcus intermedius strain XH2169]
MIELQDCLGRIFTRSQLPLGLQQQAQTLSGMIEKKEKLWCNRCGQVVNKEKQQLPIGAYYCRSCVRLGRVRSDEKLYYFP
QAEFPKTNVLKWEGRLTDYQAKVSQGLVEAVAKQKNSLVHAVTGAGKTEMIYQVVAQVINEGGAVCLASPRIDVCLELHR
RLQEDFSCDISLLHGESEVYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPMLYHAVAQSVKEKSTIIFLTATS
TDELDKKVSKGELSRLSLPRRFHGNPLIVPRKVWLENFQKYLNQKKLVPKLEQFVKKQRKTGFPLLIFASEIKRGQELAE
VLQSYFSSENVGFVASTTENRLDIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSMD
RPTGELLFFHDGTNFAIERAIQEIKAMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=892731 RYQ61_RS06365 WP_048784928.1 1228602..1229903(+) (comFA/cflA) [Streptococcus intermedius strain XH2169]
ATGATAGAATTACAAGACTGTTTAGGTCGTATCTTTACAAGAAGCCAATTACCACTAGGATTGCAGCAACAAGCTCAAAC
ATTGTCGGGAATGATAGAAAAAAAGGAGAAATTATGGTGCAATCGTTGTGGACAAGTAGTTAATAAAGAAAAACAGCAAC
TACCAATAGGTGCTTATTATTGCAGGTCATGCGTGCGATTAGGAAGGGTCAGAAGTGATGAAAAACTCTACTATTTTCCA
CAAGCAGAGTTCCCAAAAACGAATGTTTTGAAATGGGAAGGAAGGTTAACAGATTACCAAGCTAAGGTTTCTCAAGGTCT
TGTAGAGGCAGTTGCCAAACAAAAAAATAGCCTGGTTCATGCTGTCACAGGAGCAGGAAAAACAGAAATGATCTATCAAG
TGGTGGCACAAGTTATCAATGAAGGTGGTGCAGTTTGCTTGGCTAGCCCTCGAATTGATGTCTGTCTAGAACTACATCGC
AGATTGCAAGAAGATTTTAGTTGTGATATTTCACTCCTGCACGGTGAATCAGAAGTTTATTTTCGCAGTCCTCTTGTGAT
TGCCACAACGCATCAGCTTCTCAAATTTTACCGAGCATTTGATCTTCTTATTGTTGACGAGGTGGATGCCTTTCCTTATG
TGGATAATCCGATGCTTTACCATGCCGTTGCACAATCAGTAAAAGAGAAAAGTACTATAATTTTTCTAACTGCAACCTCT
ACAGATGAGCTGGATAAAAAAGTTAGCAAGGGAGAGTTGAGCCGCTTAAGTCTCCCTAGACGTTTTCATGGGAATCCTTT
AATTGTTCCTCGAAAAGTTTGGCTGGAAAATTTTCAAAAATACTTGAATCAAAAAAAGCTAGTTCCTAAGTTGGAACAAT
TTGTTAAAAAGCAAAGAAAAACAGGTTTTCCTCTTCTCATTTTTGCTTCTGAGATTAAAAGAGGACAAGAATTGGCAGAG
GTTCTCCAAAGTTATTTTTCCAGTGAGAACGTTGGCTTTGTAGCCTCAACGACTGAAAATCGACTCGATATTGTAGAGAA
ATTTCGACAAAAAGAAATTACAATTTTAGTAACAACGACAATTCTAGAACGTGGTGTGACTTTTCCTTGTGTAGATGTTT
TTGTGGTGGAGGCTAACCACCGTTTGTTTAGTCGCAGTGCTCTGGTACAAATAGCTGGACGCGTTGGTCGCAGTATGGAT
CGTCCGACAGGTGAGCTACTCTTTTTTCATGATGGGACCAATTTTGCTATTGAACGAGCTATTCAGGAAATTAAGGCGAT
GAATCAGGAGGCTGGTTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(98-245)

Helicase conserved C-terminal domain (Helicase_C)

(292-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

69.393

98.845

0.686
  comFA/cflA Streptococcus pneumoniae D39

69.393

98.845

0.686
  comFA/cflA Streptococcus pneumoniae R6

69.393

98.845

0.686
  comFA/cflA Streptococcus mitis NCTC 12261

69.484

98.383

0.684
  comFA/cflA Streptococcus pneumoniae TIGR4

69.159

98.845

0.684
  comFA/cflA Streptococcus mitis SK321

69.014

98.383

0.679
  comFA Lactococcus lactis subsp. cremoris KW2

54.02

91.917

0.497
  comFA Latilactobacillus sakei subsp. sakei 23K

40

99.307

0.397
  comFA Bacillus subtilis subsp. subtilis str. 168

39.024

94.688

0.37