Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AAC934_RS06980 Genome accession   NZ_CP152362
Coordinates   1325107..1326456 (-) Length   449 a.a.
NCBI ID   WP_041333853.1    Uniprot ID   -
Organism   Bacillus subtilis strain LP     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1320107..1331456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAC934_RS06955 (AAC934_06955) mhqA 1320287..1321237 (+) 951 WP_342625195.1 ring-cleaving dioxygenase -
  AAC934_RS06960 (AAC934_06960) - 1321346..1321441 (+) 96 Protein_1319 hypothetical protein -
  AAC934_RS06965 (AAC934_06965) ykcB 1321454..1323607 (+) 2154 WP_342625197.1 glycosyltransferase family 39 protein -
  AAC934_RS06970 (AAC934_06970) ykcC 1323619..1324590 (+) 972 WP_015715747.1 glycosyltransferase family 2 protein -
  AAC934_RS06975 (AAC934_06975) - 1324755..1324949 (-) 195 WP_033884949.1 hypothetical protein -
  AAC934_RS06980 (AAC934_06980) htrA 1325107..1326456 (-) 1350 WP_041333853.1 serine protease HtrA Regulator
  AAC934_RS06985 (AAC934_06985) proG 1326625..1327443 (+) 819 WP_088325706.1 pyrroline-5-carboxylate reductase ProG -
  AAC934_RS06990 (AAC934_06990) dppA 1327571..1328395 (+) 825 WP_014479576.1 D-aminopeptidase DppA -
  AAC934_RS06995 (AAC934_06995) dppB 1328412..1329338 (+) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  AAC934_RS07000 (AAC934_07000) dppC 1329344..1330306 (+) 963 WP_029727041.1 dipeptide ABC transporter permease DppC -
  AAC934_RS07005 (AAC934_07005) dppD 1330311..1331318 (+) 1008 WP_029727040.1 dipeptide ABC transporter ATP-binding subunit DppD -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 47744.87 Da        Isoelectric Point: 4.5990

>NTDB_id=892096 AAC934_RS06980 WP_041333853.1 1325107..1326456(-) (htrA) [Bacillus subtilis strain LP]
MDNYRDENRTKGNENEVFLTKENDQSTSYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAK
QSSSQQQTQSVTATSTSSESKKSSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG
SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGETVIA
IGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFA
IPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIIIGLK
GKEIDTGSELRNILYKDAKIGDTVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=892096 AAC934_RS06980 WP_041333853.1 1325107..1326456(-) (htrA) [Bacillus subtilis strain LP]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTAATGAGAATGAGGTCTTTTTAACGAAAGAGAACGATCAGAGCAC
CTCCTACTCGGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGCTTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTTGCCCTTGGCATTTACACGTTTACACCGCTTGGCGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCTCTGAATCTAAAAAAAGCTCAAGCAGCTC
ATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCGGTATTACAA
ATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGCGGTTCAGGG
TCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGCATCATCACT
GAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAGCCGTCCTCC
AAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTTAGAACAGGCGAGACCGTTATTGCG
ATTGGGGATCCGCTTGGAAAAGACCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAACGGTTTCAAT
GTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACAGACGCAGCAATTAATCCAGGTAACAGCGGCGGTCCTT
TGTTAAATACAGACGGCAAAATTGTCGGCATTAACAGTATGAAAATCAGTGAGGATGATGTTGAGGGTATCGGATTCGCC
ATTCCAAGCAATGACGTAAAACCGATTGCTGAGGAATTGCTGTCTAAAGGACAAATTGAACGTCCATATATCGGTGTCAG
CATGCTTGATCTGGAACAAGTGCCGCAAAACTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGAATAAAGGTG
TTTACATCCGTGAGGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCGGAGGATATTATCATCGGCCTAAAA
GGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGATACCGTTGAAGTGAA
AATTCTTCGAAACGGCAAAGAAATGACGAAAAAAATTAAACTTGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(342-441)

Trypsin-like peptidase domain (Trypsin_2)

(160-304)

Peptidase family M50 (Peptidase_M50)

(366-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

41.045

89.532

0.367
  htrA Streptococcus pneumoniae D39

41.045

89.532

0.367
  htrA Streptococcus pneumoniae R6

41.045

89.532

0.367
  htrA Streptococcus pneumoniae TIGR4

41.045

89.532

0.367
  htrA Streptococcus mitis NCTC 12261

39.563

91.759

0.363