Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   F6I35_RS05455 Genome accession   NZ_CP136160
Coordinates   1047080..1049308 (-) Length   742 a.a.
NCBI ID   WP_024051600.1    Uniprot ID   A0A412PQ79
Organism   Streptococcus anginosus strain UMB8616     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1042080..1054308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS05430 (F6I35_0005430) - 1042348..1043625 (-) 1278 WP_070815179.1 dihydroorotase -
  F6I35_RS05435 (F6I35_0005435) - 1043638..1044108 (-) 471 WP_024051595.1 NUDIX hydrolase -
  F6I35_RS05440 (F6I35_0005440) - 1044145..1044798 (-) 654 WP_024051596.1 uracil-DNA glycosylase -
  F6I35_RS05445 (F6I35_0005445) - 1044822..1045808 (-) 987 WP_024051597.1 Gfo/Idh/MocA family protein -
  F6I35_RS05450 (F6I35_0005450) - 1046438..1046998 (-) 561 WP_224783657.1 DUF805 domain-containing protein -
  F6I35_RS05455 (F6I35_0005455) comEC/celB 1047080..1049308 (-) 2229 WP_024051600.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  F6I35_RS05460 (F6I35_0005460) comEA/celA/cilE 1049292..1049996 (-) 705 WP_024051601.1 helix-hairpin-helix domain-containing protein Machinery gene
  F6I35_RS05465 (F6I35_0005465) smpB 1050179..1050646 (-) 468 WP_024051602.1 SsrA-binding protein SmpB -
  F6I35_RS05470 (F6I35_0005470) rnr 1050609..1052948 (-) 2340 WP_101750372.1 ribonuclease R -
  F6I35_RS05475 (F6I35_0005475) secG 1053040..1053273 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -
  F6I35_RS05480 (F6I35_0005480) rpmG 1053313..1053462 (-) 150 WP_003024746.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 85068.91 Da        Isoelectric Point: 9.9918

>NTDB_id=888969 F6I35_RS05455 WP_024051600.1 1047080..1049308(-) (comEC/celB) [Streptococcus anginosus strain UMB8616]
MSQWIKKFPIKPIYIAFLLVWLYFAIYPSSWLGWLGFIFLVIRLFRFYSPKECFMTFMILSCFASFFFIRREIAEQQTKA
EPSPIKQVAVLPDTIKVNGDSLSFRGKANRQTYQVYHKLKSKEEQLAFQNLSSLVALTVEGDFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDRISLHPLEWLSSWRRKALVFIKNHFPNPMSNYMTGLLFGALDTDFDEMSNLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLRLGFTQEMVRKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLSAGGVLSCVYAFVISVIDFEGLASWRKVVVESSVISLGILPILIFYFGEFQPWSILLTFVFSLIFDAMMLPGLT
LIFLFSPLIKLTQVNFLFEGLENSIRWIASVFGKPIVFGQPSPLLLIVMLLVLAILYDVRKNKKWVIFLSLFLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGKNVLIDVGGREEIRTKEAWQKRAISSNAEKTLIPYLKSRGVDTIDTLVLTNPNP
DYAGDVLGVAKKFAIKKIYISRSSLSNADFLEKLRKLNTFIHVVKQGDKLPIFDHHLQVLSGVSKNDHSIVLYGQFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHEAKDSSSSKFLQQIEPTVALISVEKNNQSKQPSQDTIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=888969 F6I35_RS05455 WP_024051600.1 1047080..1049308(-) (comEC/celB) [Streptococcus anginosus strain UMB8616]
ATGTCACAGTGGATTAAAAAATTTCCGATTAAGCCGATTTACATTGCTTTCTTACTTGTCTGGTTATATTTTGCAATCTA
TCCAAGTAGCTGGTTAGGCTGGTTGGGTTTTATCTTTCTGGTAATTCGTCTTTTTCGCTTTTATTCACCGAAAGAATGTT
TCATGACCTTCATGATCCTCTCTTGTTTTGCTAGTTTTTTCTTTATTCGTAGGGAAATAGCAGAGCAGCAAACAAAAGCA
GAGCCTTCTCCCATAAAACAAGTGGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCGCTTTCTTTTCGTGGTAA
AGCTAATAGGCAGACTTATCAAGTTTACCACAAATTGAAATCAAAGGAAGAGCAGTTGGCTTTTCAAAATCTCTCTAGTT
TGGTTGCGTTGACCGTTGAAGGAGATTTTGAAATTCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCTTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTAGATACCATTTTATCGAGCCAAGATAGAATCAGCTTGCACCCTTT
GGAGTGGCTCTCTAGCTGGCGAAGAAAGGCACTGGTATTTATCAAGAACCATTTTCCAAATCCGATGAGTAATTATATGA
CGGGGCTCTTATTTGGCGCCTTGGATACAGACTTTGACGAAATGAGCAATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGCTTTTTTATGGAGGGATTTCGCAAGTTACTGTTAAGGCTGGGGTTCACACAAGA
AATGGTTCGTAAATGCCAATATCCATTTTCTTTCTTTTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAGTTCAGAAATTATTATCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCGTCCTTTCTTTTGTCGGCAGGAGGAGTTCTCTCCTGTGTCTATGCTTTTGTCATTAGTGTGATAGATTTTGAAGG
TCTGGCTTCTTGGCGAAAAGTTGTTGTAGAGAGTAGCGTTATTTCACTTGGTATTTTACCGATTCTAATCTTTTACTTTG
GCGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTGATTTTTGATGCAATGATGTTGCCAGGCTTGACG
TTAATTTTTCTTTTTTCGCCTTTGATAAAGTTGACTCAAGTCAATTTTCTATTTGAAGGTTTAGAAAATAGTATTCGTTG
GATAGCAAGTGTCTTTGGTAAACCAATCGTTTTTGGGCAGCCCAGTCCGCTTTTGCTGATTGTTATGCTGCTTGTACTGG
CTATTTTGTATGATGTTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTCTGTTTCTTTCATTACTCTTTTTCATAAAT
AAATTTCCTTTGCAAAACGAGATCACAATGGTGGATGTCGGGCAAGGAGATAGTATTTTTCTGAGAGACTGGAAAGGAAA
AAATGTATTGATTGATGTTGGCGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCAATTAGCTCAAATG
CAGAAAAAACTTTGATTCCTTATCTAAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGGAGTTGCTAAAAAGTTTGCAATAAAAAAAATTTATATTTCCAGAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAACTAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCGGGTGTTAGCAAGAACGACCATTCGATCGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCAAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGAAGCCAAGGACTCATCAAGTTCAAAATTTTTGCAACAAATAGAACCAACGGTTGCGCTCATTT
CTGTTGAGAAAAATAATCAATCTAAGCAACCTAGTCAAGATACAATAGAGCGATTTGCACAATTGCCTGCTAAAGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(216-460)

Domain of unknown function (DUF4131) (DUF4131)

(28-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PQ79

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.618

100

0.55
  comEC/celB Streptococcus mitis NCTC 12261

53.887

100

0.542
  comEC/celB Streptococcus pneumoniae TIGR4

53.548

100

0.539
  comEC/celB Streptococcus pneumoniae Rx1

52.744

100

0.531
  comEC/celB Streptococcus pneumoniae D39

52.744

100

0.531
  comEC/celB Streptococcus pneumoniae R6

52.744

100

0.531
  comEC Lactococcus lactis subsp. cremoris KW2

47.517

100

0.477