Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   F6I35_RS02750 Genome accession   NZ_CP136160
Coordinates   495124..495783 (-) Length   219 a.a.
NCBI ID   WP_024052075.1    Uniprot ID   A0A412PLC5
Organism   Streptococcus anginosus strain UMB8616     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 490124..500783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS02730 (F6I35_0002730) - 491185..491748 (+) 564 WP_024052080.1 YutD family protein -
  F6I35_RS02735 (F6I35_0002735) rlmN 491789..492871 (+) 1083 WP_024052079.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  F6I35_RS02740 (F6I35_0002740) - 492864..493394 (+) 531 WP_024052078.1 VanZ family protein -
  F6I35_RS02745 (F6I35_0002745) trpB 493755..494963 (+) 1209 Protein_500 tryptophan synthase subunit beta -
  F6I35_RS02750 (F6I35_0002750) cclA/cilC 495124..495783 (-) 660 WP_024052075.1 prepilin peptidase Machinery gene
  F6I35_RS02755 (F6I35_0002755) - 495937..496464 (+) 528 WP_003032411.1 Dps family protein -
  F6I35_RS02760 (F6I35_0002760) - 496738..496962 (+) 225 WP_003025724.1 YqgQ family protein -
  F6I35_RS02765 (F6I35_0002765) - 496956..497336 (+) 381 WP_024052074.1 rhodanese-like domain-containing protein -
  F6I35_RS02770 (F6I35_0002770) - 497357..498082 (-) 726 WP_024052073.1 16S rRNA pseudouridine(516) synthase -
  F6I35_RS02775 (F6I35_0002775) typA 498260..500101 (+) 1842 WP_150866971.1 translational GTPase TypA -
  F6I35_RS02780 (F6I35_0002780) - 500166..500450 (+) 285 WP_024052072.1 DUF3165 family protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24887.36 Da        Isoelectric Point: 8.2951

>NTDB_id=888952 F6I35_RS02750 WP_024052075.1 495124..495783(-) (cclA/cilC) [Streptococcus anginosus strain UMB8616]
MIHFYFFLVGSIVASFLGLVVDRFPEQSIIVPSSHCNACGQKLAPRDLVPVLSQLINRLRCRFCQSKIPIRYLILELVGS
LLFLATSLSYLTISQLVLLIMGITLALYDQREQEYPILIWLFFHLLLLFLVGFNLLMISFLALGIVAFFFDLRIGAGDFL
FLASCSTVFKLTEILWLIQIASLVGLCLFCLKKRKDRIAFVPCLLIGVIVLLMYELLLQ

Nucleotide


Download         Length: 660 bp        

>NTDB_id=888952 F6I35_RS02750 WP_024052075.1 495124..495783(-) (cclA/cilC) [Streptococcus anginosus strain UMB8616]
ATGATTCATTTTTATTTTTTCTTGGTTGGAAGCATTGTGGCTTCTTTTTTAGGGCTGGTTGTTGATCGCTTTCCTGAACA
GTCCATTATCGTTCCTTCCAGTCATTGTAATGCTTGTGGGCAGAAATTAGCACCTCGTGATTTAGTCCCTGTCCTTTCAC
AGCTTATCAATCGACTGCGCTGTCGGTTTTGTCAGTCAAAAATTCCCATTCGCTACTTGATATTAGAGTTGGTAGGTAGT
TTACTCTTTCTCGCAACTTCCTTAAGCTACTTAACTATCAGCCAACTTGTCTTGCTCATAATGGGAATTACACTAGCTCT
TTATGATCAAAGAGAACAGGAATATCCTATCCTCATTTGGTTGTTCTTTCATCTTCTTCTCCTATTTTTGGTAGGTTTTA
ATCTTCTAATGATTAGTTTTTTAGCCCTTGGAATAGTAGCTTTTTTCTTTGACTTACGAATTGGCGCAGGAGACTTTCTT
TTTCTAGCTTCTTGTTCAACTGTTTTCAAGTTGACAGAGATTCTTTGGCTGATTCAAATTGCCAGCTTAGTGGGCTTATG
TCTCTTTTGCTTAAAAAAGAGAAAAGACAGGATAGCTTTCGTTCCCTGTCTTTTGATTGGAGTGATTGTTCTACTTATGT
ATGAGTTGTTACTTCAATAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PLC5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis NCTC 12261

56.422

99.543

0.562
  cclA/cilC Streptococcus mitis SK321

56.422

99.543

0.562
  cclA/cilC Streptococcus pneumoniae Rx1

56.422

99.543

0.562
  cclA/cilC Streptococcus pneumoniae D39

56.422

99.543

0.562
  cclA/cilC Streptococcus pneumoniae R6

56.422

99.543

0.562
  cclA/cilC Streptococcus pneumoniae TIGR4

55.505

99.543

0.553