Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   RSK81_RS08565 Genome accession   NZ_CP135591
Coordinates   1740473..1741819 (-) Length   448 a.a.
NCBI ID   WP_002894938.1    Uniprot ID   A0A3R9HU52
Organism   Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1735473..1746819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RSK81_RS08550 (RSK81_08550) rnc 1738392..1739090 (-) 699 WP_002903151.1 ribonuclease III -
  RSK81_RS08555 (RSK81_08555) - 1739212..1739571 (-) 360 WP_002906095.1 YbaN family protein -
  RSK81_RS08560 (RSK81_08560) vicX 1739663..1740463 (-) 801 WP_002914756.1 MBL fold metallo-hydrolase Regulator
  RSK81_RS08565 (RSK81_08565) micB 1740473..1741819 (-) 1347 WP_002894938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RSK81_RS08570 (RSK81_08570) micA 1741812..1742513 (-) 702 WP_002894937.1 response regulator YycF Regulator
  RSK81_RS08575 (RSK81_08575) - 1742854..1743615 (+) 762 WP_032913415.1 amino acid ABC transporter ATP-binding protein -
  RSK81_RS08580 (RSK81_08580) - 1743630..1744442 (+) 813 WP_002906091.1 transporter substrate-binding domain-containing protein -
  RSK81_RS08585 (RSK81_08585) - 1744455..1745135 (+) 681 WP_002906090.1 amino acid ABC transporter permease -
  RSK81_RS08590 (RSK81_08590) - 1745146..1745805 (+) 660 WP_002912899.1 amino acid ABC transporter permease -
  RSK81_RS08595 (RSK81_08595) - 1745914..1746312 (+) 399 WP_002897198.1 hypothetical protein -
  RSK81_RS08600 (RSK81_08600) - 1746351..1746728 (-) 378 WP_002899930.1 carboxymuconolactone decarboxylase family protein -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 50860.77 Da        Isoelectric Point: 4.4112

>NTDB_id=887039 RSK81_RS08565 WP_002894938.1 1740473..1741819(-) (micB) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
MIEAIKQFVISADFVFAIIIIGFIVVVALLLLENRRDNQKLVQLNQKVKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDEVQNMSILDLLSISDEYDLRDLITNVPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSHLEVELTNFTAFITFILNRFDKIKNQDETKKYEIIRDYPITPIW
VEIDTDKLTQVIDNIMNNAIKYSPDGGTITVSIKTTDEQLILSIADEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGVGSTFTIVLPYENDGVRDDDWDNEDI

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=887039 RSK81_RS08565 WP_002894938.1 1740473..1741819(-) (micB) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
ATGATTGAAGCAATTAAACAATTTGTGATTTCTGCGGATTTTGTCTTTGCAATCATTATTATCGGCTTCATTGTAGTTGT
TGCCTTGCTTTTATTGGAAAATCGCCGGGATAATCAAAAGCTTGTACAGCTTAATCAAAAGGTTAAAGATTTGATTGCAG
GTGACTATTCTGAAGTGCTGGACATGCAAGGGAGTCCAGAAATCACAGATATGACCAACAGTATCAATGATCTTTCAGAG
GTCATTCGACTGACACATGAAAACCTTGAGCAAGAAACAAAACGCCTTTCCAGTATCCTGTCCTATATGACAGATGGCGT
GCTTGCGACTAACCGCCGGGGGCAGATTATCACTATCAACGATATGGCAACCAAGCAGTTGGGAGTTAAGAGAGATGAGG
TCCAAAATATGAGTATTTTGGATCTGCTTTCGATTTCAGACGAGTATGATTTGCGGGACCTGATTACCAATGTTCCTGAG
CTGACGATTGATTCTCAGGATGAAAATGGTGAGTACTTGAGTTTGCGGGTTCGCTTTGCCTTGGTAAGGCGGGAGTCGGG
CTTTATTTCTGGTTTGGTAGCTGTCTTGCATGATACGACAGAGCAGGATAAGGAAGAGCGGGAGCGTCGCCTCTTTGTCT
CCAACGTCAGCCATGAGTTGCGGACTCCGCTGACCAGTGTTAAGTCCTATCTGGAAGCCCTGGATGAGGGAGCTTTGTCT
GAGCCAGTAGCACCGGACTTTGTCAAGGTATCGCTCAATGAAACCAACCGCATGATGCGGATGGTGACGGACTTGCTTAG
TCTGTCCCGTATTGATAATGAGACCAGCCATCTGGAAGTGGAGTTGACGAACTTCACGGCCTTTATTACCTTTATCCTCA
ATCGCTTTGACAAGATAAAAAATCAAGACGAAACTAAGAAATATGAGATTATCCGTGATTATCCTATAACACCGATCTGG
GTAGAGATTGATACAGATAAGCTGACCCAGGTCATTGATAATATCATGAACAATGCCATCAAGTATTCGCCGGATGGTGG
AACCATTACTGTTTCCATCAAGACAACGGATGAGCAGTTGATTCTCTCTATTGCAGACGAGGGACTAGGAATTCCCAAGC
AGGACTTGCCTAAGATTTTTGATCGCTTTTATCGAGTGGACAAGGCACGCAGCCGCGCACAGGGCGGAACGGGTCTGGGG
CTGGCTATTGCCAAGGAAATTATCAAGCAGCATCAGGGCTTTATCTGGGCTAAGAGTGAGTATGGTGTGGGCTCGACCTT
TACCATTGTCTTGCCTTATGAGAATGATGGCGTCCGGGATGACGACTGGGATAATGAAGATATATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9HU52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

97.991

0.77
  vicK Streptococcus mutans UA159

70.72

89.955

0.636