Detailed information NTG0887023

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: RSK81_RS03190
• Genome accession: NZ_CP135591
• Coordinates: 625195..625857 (-)
• Length: 220 a.a.
• NCBI ID: WP_002925573.1
• Uniprot ID: A0A2X3VKV0
• Organism: Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 620195..630857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RSK81_RS03160 (RSK81_03160)	-	620325..620888 (+)	564	WP_002925580.1	aminodeoxychorismate/anthranilate synthase component II	-
RSK81_RS03165 (RSK81_03165)	trpD	620899..621903 (+)	1005	WP_002925579.1	anthranilate phosphoribosyltransferase	-
RSK81_RS03170 (RSK81_03170)	trpC	621900..622667 (+)	768	WP_315687404.1	indole-3-glycerol phosphate synthase TrpC	-
RSK81_RS03175 (RSK81_03175)	-	622654..623241 (+)	588	WP_101771128.1	phosphoribosylanthranilate isomerase	-
RSK81_RS03180 (RSK81_03180)	trpB	623231..624454 (+)	1224	WP_002925576.1	tryptophan synthase subunit beta	-
RSK81_RS03185 (RSK81_03185)	trpA	624447..625226 (+)	780	WP_315687406.1	tryptophan synthase subunit alpha	-
RSK81_RS03190 (RSK81_03190)	cclA/cilC	625195..625857 (-)	663	WP_002925573.1	prepilin peptidase	Machinery gene
RSK81_RS03195 (RSK81_03195)	-	626024..626539 (+)	516	WP_002898046.1	Dps family protein	-
RSK81_RS03200 (RSK81_03200)	-	626632..626850 (+)	219	WP_002898045.1	YqgQ family protein	-
RSK81_RS03205 (RSK81_03205)	-	626852..627232 (+)	381	WP_002904037.1	rhodanese-like domain-containing protein	-
RSK81_RS03210 (RSK81_03210)	-	627322..627561 (+)	240	WP_101771131.1	DUF4190 domain-containing protein	-
RSK81_RS03215 (RSK81_03215)	-	627594..628319 (-)	726	WP_125330355.1	pseudouridine synthase	-
RSK81_RS03220 (RSK81_03220)	typA	628500..630347 (+)	1848	WP_002932699.1	translational GTPase TypA	-
RSK81_RS03225 (RSK81_03225)	-	630371..630640 (+)	270	WP_002898040.1	DUF3165 family protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 24649.92 Da
• Isoelectric Point: 8.9310

>NTDB_id=887023 RSK81_RS03190 WP_002925573.1 625195..625857(-) (cclA/cilC) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
MIHLYFFLLGTVFASFLGLVIDRFPERSVISPASHCNACGKRLAPRDLIPIFSQAMNRLRCRFCGDKIPLRYLFFECLLG
GLFLATSLSILSISQLLVVTMGLTLAIYDQREQQYPLMIWLVFQLLLLMTAGVNLLILFFLALGLLAFFYNLRIGAGDFL
FLASCSAIFSLTETLILIQIASFSGLACFCFKKKKDRLAFVPCLLFGAVVIISYKLLLLG

Nucleotide

• Length: 663 bp

>NTDB_id=887023 RSK81_RS03190 WP_002925573.1 625195..625857(-) (cclA/cilC) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
ATGATTCATCTATACTTTTTTCTACTTGGCACTGTCTTTGCTTCATTCCTAGGCTTGGTCATCGACCGCTTCCCAGAGCG
GTCTGTCATCTCTCCCGCTAGTCATTGCAATGCCTGCGGGAAAAGATTAGCACCGCGTGATTTGATTCCTATTTTTTCCC
AAGCCATGAACCGGCTTCGTTGCCGCTTCTGCGGAGACAAGATTCCCTTACGCTATTTATTTTTTGAATGTCTCTTGGGC
GGTCTTTTTCTGGCAACTTCTCTGAGCATTCTTTCCATTAGTCAATTATTGGTAGTCACCATGGGCTTAACCTTAGCTAT
CTACGATCAAAGAGAGCAGCAATACCCTTTGATGATCTGGTTGGTTTTTCAGCTTTTGCTGCTAATGACAGCAGGCGTTA
ATCTTCTCATACTCTTCTTTTTAGCCTTAGGACTTCTAGCCTTCTTTTATAATCTTCGTATTGGAGCTGGTGACTTTCTC
TTTCTGGCGTCTTGCTCAGCCATTTTCAGCCTGACGGAGACTCTCATCCTTATCCAAATCGCTAGTTTCTCTGGCCTCGC
CTGTTTCTGCTTTAAAAAGAAAAAAGACAGGCTAGCATTTGTACCTTGTCTTTTGTTTGGTGCGGTGGTGATTATTTCTT
ATAAGCTGCTGCTTCTTGGATAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-88)

3D structure

• AlphaFold DB: A0A2X3VKV0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis NCTC 12261	58.904	99.545	0.586
cclA/cilC	Streptococcus mitis SK321	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae Rx1	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae D39	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae R6	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae TIGR4	56.621	99.545	0.564