Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RRU92_RS05800 Genome accession   NZ_CP135436
Coordinates   1202768..1204102 (+) Length   444 a.a.
NCBI ID   WP_315638905.1    Uniprot ID   A0AA96MNS8
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1197768..1209102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS05780 (RRU92_05780) - 1198034..1198882 (+) 849 WP_315638902.1 putative PEP-binding protein -
  RRU92_RS05785 (RRU92_05785) - 1198879..1199319 (+) 441 WP_315638903.1 ASCH domain-containing protein -
  RRU92_RS05790 (RRU92_05790) - 1199442..1201988 (+) 2547 WP_315640913.1 M1 family metallopeptidase -
  RRU92_RS05795 (RRU92_05795) ciaR 1202104..1202775 (+) 672 WP_075229131.1 response regulator transcription factor Regulator
  RRU92_RS05800 (RRU92_05800) ciaH 1202768..1204102 (+) 1335 WP_315638905.1 HAMP domain-containing sensor histidine kinase Regulator
  RRU92_RS05805 (RRU92_05805) - 1204210..1204485 (-) 276 WP_070460932.1 DUF3270 family protein -
  RRU92_RS05810 (RRU92_05810) - 1204624..1205553 (+) 930 WP_315638907.1 peptidase U32 family protein -
  RRU92_RS05815 (RRU92_05815) rpiA 1205659..1206342 (+) 684 WP_315638909.1 ribose-5-phosphate isomerase RpiA -
  RRU92_RS05820 (RRU92_05820) - 1206371..1207582 (+) 1212 WP_315638911.1 phosphopentomutase -
  RRU92_RS05825 (RRU92_05825) - 1207584..1208144 (+) 561 WP_315638913.1 DUF1697 domain-containing protein -
  RRU92_RS05830 (RRU92_05830) - 1208141..1208950 (+) 810 WP_315638914.1 purine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 50492.92 Da        Isoelectric Point: 8.9123

>NTDB_id=886546 RRU92_RS05800 WP_315638905.1 1202768..1204102(+) (ciaH) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MFNKFKKNWYAEDFSYFIRNFGVFTLIFSAMTLIILQVMHSSLYTSVDEKLLSLSKNPQDVIQLAVNRATEDVKDLGSAN
VAPASDKKPTVSSNTEVILLDSNLNQLVTGNRFLGLDKITFNKKDLNHIRQLHVQNSYGQDEIYRVILSEINIDSVSTNI
KYAAVLINTSQIEQISQNHEQLIVVVMASFWILSIIASLYLARVSVKPLLESMQKQQSFVENASHELRTPLAVLQNRLET
LFRKPEATIMESSESIASSLEEVRNMRFLTTNLLNLARRDDGINPELGEVQPDFFNTTFTNYEMIASENNRVFHFENRIH
RTIITDKLLLKQLMTILFDNAVKYTEEEGDIHFVIATTERNLYLSVADDGIGISAVDKKKIFDRFYRVDKARTRQKGGFG
LGLSLAKQIVDALKGTISVKDNKPHGTIFEVKIAIQTPSKRKNK

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=886546 RRU92_RS05800 WP_315638905.1 1202768..1204102(+) (ciaH) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGTTTAATAAATTTAAAAAGAATTGGTATGCGGAGGATTTCAGTTATTTTATCCGTAACTTTGGAGTATTTACTCTGAT
TTTCTCTGCTATGACCTTGATTATCTTACAGGTTATGCACTCCAGTCTCTACACATCGGTGGATGAAAAACTCTTATCAC
TGAGCAAAAATCCTCAGGACGTCATTCAATTGGCGGTCAATCGTGCAACTGAGGACGTTAAGGATTTAGGTAGTGCCAAT
GTTGCTCCAGCTTCTGATAAAAAACCAACGGTTAGTTCCAATACGGAAGTGATATTGCTAGATTCAAATTTGAATCAATT
AGTGACTGGCAACCGCTTTTTAGGTCTTGATAAGATTACTTTTAATAAAAAGGATTTGAATCATATTCGACAACTTCATG
TTCAGAATAGTTATGGTCAGGATGAGATTTACCGAGTGATTCTATCTGAAATAAATATCGATTCTGTCTCGACCAATATT
AAGTATGCAGCGGTTTTGATAAATACCAGTCAGATAGAGCAAATTAGTCAAAATCATGAGCAATTAATCGTGGTAGTCAT
GGCTAGCTTCTGGATTTTATCCATTATTGCCAGCCTTTATCTTGCGCGTGTCAGTGTTAAACCTTTACTTGAAAGCATGC
AAAAGCAACAGAGTTTTGTGGAAAATGCCAGTCATGAGCTACGAACTCCATTAGCTGTTCTGCAAAATCGTCTAGAAACT
CTTTTTCGAAAGCCGGAAGCTACTATTATGGAATCTAGCGAGAGTATTGCTTCTAGTTTAGAAGAAGTTCGAAACATGCG
CTTTTTAACAACCAATCTCCTAAATTTAGCCCGTCGTGATGATGGTATCAATCCTGAACTAGGAGAGGTACAGCCAGACT
TCTTTAACACAACCTTTACCAACTATGAAATGATTGCGTCTGAAAATAACCGCGTTTTTCATTTTGAAAATCGCATCCAT
CGGACCATCATAACAGATAAGCTTCTTCTTAAACAACTGATGACTATCTTGTTTGACAATGCTGTCAAGTACACAGAAGA
AGAAGGAGATATCCATTTTGTCATTGCTACGACGGAGCGTAATCTCTATTTGTCAGTAGCTGATGATGGAATTGGTATTT
CTGCAGTAGATAAAAAGAAAATTTTTGATCGCTTTTACAGGGTTGATAAGGCTCGTACTCGGCAAAAAGGTGGTTTTGGG
TTAGGCTTATCCTTAGCCAAACAGATTGTCGATGCTCTTAAAGGAACCATCAGTGTCAAAGATAACAAACCTCATGGTAC
GATTTTTGAAGTAAAAATCGCTATCCAAACACCATCCAAGCGTAAAAATAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-433)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

82.619

99.775

0.824
  ciaH Streptococcus pneumoniae D39

82.619

99.775

0.824
  ciaH Streptococcus pneumoniae R6

82.619

99.775

0.824
  ciaH Streptococcus pneumoniae TIGR4

82.619

99.775

0.824
  ciaH Streptococcus mutans UA159

55.963

98.198

0.55