NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	MGAS37844_RS08925	Genome accession	NZ_CP151450
Coordinates	1769217..1769813 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain MGAS37844
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1764217..1774813

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37844_RS08890 (MGAS37844_03650)	-	1764278..1764583 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
MGAS37844_RS08895 (MGAS37844_03652)	ruvX	1764595..1765014 (-)	420	WP_010922752.1	Holliday junction resolvase RuvX	-
MGAS37844_RS08900 (MGAS37844_03654)	-	1765011..1765280 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
MGAS37844_RS08905 (MGAS37844_03658)	spx	1765393..1765791 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
MGAS37844_RS08910 (MGAS37844_03660)	recA	1766082..1767218 (-)	1137	WP_010922753.1	recombinase RecA	Machinery gene
MGAS37844_RS08915 (MGAS37844_03662)	cinA	1767307..1768578 (-)	1272	WP_010922754.1	competence/damage-inducible protein A	Machinery gene
MGAS37844_RS08920 (MGAS37844_03664)	-	1768647..1769207 (-)	561	WP_010922755.1	DNA-3-methyladenine glycosylase I	-
MGAS37844_RS08925 (MGAS37844_03666)	ruvA	1769217..1769813 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
MGAS37844_RS08930 (MGAS37844_03668)	-	1769815..1771035 (-)	1221	WP_010922756.1	MFS transporter	-
MGAS37844_RS08935 (MGAS37844_03670)	hexB	1771046..1773028 (-)	1983	WP_010922757.1	DNA mismatch repair endonuclease MutL	Machinery gene

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=886458 MGAS37844_RS08925 WP_002992186.1 1769217..1769813(-) (ruvA) [Streptococcus pyogenes strain MGAS37844]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=886458 MGAS37844_RS08925 WP_002992186.1 1769217..1769813(-) (ruvA) [Streptococcus pyogenes strain MGAS37844]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGGTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCTCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG0886458