Detailed information NTG0885448

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: QN339_RS10310
• Genome accession: NZ_CP135104
• Coordinates: 2055681..2056910 (+)
• Length: 409 a.a.
• NCBI ID: WP_395083315.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain MA15
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2050681..2061910

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN339_RS10285 (QN339_10270)	-	2051843..2054422 (+)	2580	WP_000154429.1	YfhO family protein	-
QN339_RS10305 (QN339_10290)	rlmH	2055001..2055480 (-)	480	WP_000768333.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
QN339_RS10310 (QN339_10295)	htrA	2055681..2056910 (+)	1230	WP_395083315.1	S1C family serine protease	Regulator
QN339_RS10315 (QN339_10300)	spo0J	2057008..2057781 (+)	774	WP_000456084.1	ParB/RepB/Spo0J family partition protein	Regulator
QN339_RS10320 (QN339_10305)	dnaA	2057980..2059341 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
QN339_RS10325 (QN339_10310)	dnaN	2059496..2060632 (+)	1137	WP_000581133.1	DNA polymerase III subunit beta	-
QN339_RS10330 (QN339_10315)	-	2060690..2061582 (+)	893	Protein_1995	diacylglycerol/lipid kinase family protein	-
QN339_RS10335 (QN339_10320)	-	2061592..2061789 (+)	198	WP_000285199.1	DUF951 domain-containing protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43117.56 Da
• Isoelectric Point: 9.5271

>NTDB_id=885448 QN339_RS10310 WP_395083315.1 2055681..2056910(+) (htrA) [Streptococcus agalactiae strain MA15]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNNVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=885448 QN339_RS10310 WP_395083315.1 2055681..2056910(+) (htrA) [Streptococcus agalactiae strain MA15]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGAGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCCGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAAGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAACGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• Peptidase family M50 (Peptidase_M50) (279-400)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.359	96.088	0.609
htrA	Streptococcus gordonii str. Challis substr. CH1	57.107	98.044	0.56
htrA	Streptococcus mitis NCTC 12261	56.281	97.311	0.548
htrA	Streptococcus pneumoniae TIGR4	54.791	99.511	0.545
htrA	Streptococcus pneumoniae Rx1	54.791	99.511	0.545
htrA	Streptococcus pneumoniae D39	54.791	99.511	0.545
htrA	Streptococcus pneumoniae R6	54.791	99.511	0.545