Detailed information NTG0885387

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: QN329_RS08955
• Genome accession: NZ_CP135103
• Coordinates: 1744714..1746951 (-)
• Length: 745 a.a.
• NCBI ID: WP_161512872.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain HU36/21
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1739714..1751951

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN329_RS08930 (QN329_08935)	holA	1739779..1740816 (-)	1038	WP_000560292.1	DNA polymerase III subunit delta	-
QN329_RS08935 (QN329_08940)	-	1740870..1741598 (-)	729	WP_000468967.1	methyltransferase domain-containing protein	-
QN329_RS08940 (QN329_08945)	-	1741774..1742766 (+)	993	WP_000800991.1	alpha/beta hydrolase fold domain-containing protein	-
QN329_RS08945 (QN329_08950)	-	1742825..1743769 (-)	945	WP_000200826.1	LacI family DNA-binding transcriptional regulator	-
QN329_RS08950 (QN329_08955)	-	1743780..1744589 (-)	810	WP_000153216.1	Cof-type HAD-IIB family hydrolase	-
QN329_RS08955 (QN329_08960)	comEC/celB	1744714..1746951 (-)	2238	WP_161512872.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
QN329_RS08960 (QN329_08965)	-	1746935..1747588 (-)	654	WP_000461740.1	helix-hairpin-helix domain-containing protein	-
QN329_RS08965 (QN329_08970)	-	1747687..1748427 (-)	741	WP_000500221.1	lysophospholipid acyltransferase family protein	-
QN329_RS08970 (QN329_08975)	-	1748562..1749326 (+)	765	WP_000567424.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
QN329_RS08975 (QN329_08980)	-	1749319..1749585 (+)	267	WP_000598736.1	GIY-YIG nuclease family protein	-
QN329_RS08980 (QN329_08985)	-	1749770..1751356 (-)	1587	WP_000673086.1	DEAD/DEAH box helicase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85398.25 Da
• Isoelectric Point: 9.7775

>NTDB_id=885387 QN329_RS08955 WP_161512872.1 1744714..1746951(-) (comEC/celB) [Streptococcus agalactiae strain HU36/21]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDRETIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIEVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLSQHRSFFALMSKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDNMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLGCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRLRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDDLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKIAVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=885387 QN329_RS08955 WP_161512872.1 1744714..1746951(-) (comEC/celB) [Streptococcus agalactiae strain HU36/21]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTGAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATCATTGCAGATATCAAACTCGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATCTCAACATAGGTCTTTCTT
TGCTCTTATGTCTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GACTTTTGTTTGGATATCTAGATAAGACCTTTGATAACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAGGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTGTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTCGCGATTTTAGATGTTGGACAAGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGTTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGCATTAGCAAGATAGATGATTTAGTGATAACTCACACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGTGTAGCGGTAAAATCTATAGAAGCCGGTGATAAAATTGCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGCACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-694)

• Domain of unknown function (DUF4131) (DUF4131) (28-177)

• Competence protein (Competence) (215-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.602	100	0.49
comEC/celB	Streptococcus mitis NCTC 12261	48.267	100	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	47.004	100	0.474
comEC/celB	Streptococcus pneumoniae Rx1	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.533	100	0.468
comEC	Lactococcus lactis subsp. cremoris KW2	44.28	99.732	0.442