Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   QN329_RS02050 Genome accession   NZ_CP135103
Coordinates   348378..349289 (-) Length   303 a.a.
NCBI ID   WP_000912100.1    Uniprot ID   A0A0E1EEL0
Organism   Streptococcus agalactiae strain HU36/21     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 343378..354289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN329_RS02030 (QN329_02030) - 344332..346110 (-) 1779 WP_161512838.1 acyltransferase family protein -
  QN329_RS02035 (QN329_02035) - 346107..346487 (-) 381 WP_000787702.1 membrane protein -
  QN329_RS02040 (QN329_02040) - 346494..346931 (-) 438 WP_000754818.1 low molecular weight protein-tyrosine-phosphatase -
  QN329_RS02045 (QN329_02045) ruvB 347083..348081 (-) 999 WP_000196633.1 Holliday junction branch migration DNA helicase RuvB -
  QN329_RS02050 (QN329_02050) comR 348378..349289 (-) 912 WP_000912100.1 helix-turn-helix domain-containing protein Regulator
  QN329_RS02055 (QN329_02055) purB 349442..350741 (-) 1300 Protein_363 adenylosuccinate lyase -
  QN329_RS02060 (QN329_02060) - 350766..352156 (-) 1391 Protein_364 hypothetical protein -
  QN329_RS02065 (QN329_02065) purK 352209..353300 (-) 1092 WP_410531526.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  QN329_RS02070 (QN329_02070) purE 353287..353775 (-) 489 WP_410531635.1 5-(carboxyamino)imidazole ribonucleotide mutase -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35654.11 Da        Isoelectric Point: 5.6370

>NTDB_id=885364 QN329_RS02050 WP_000912100.1 348378..349289(-) (comR) [Streptococcus agalactiae strain HU36/21]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YLILRIPTYADAERLKLRECQFDHIFEEFYDNLPEDECLAIDSLQAKFEVYQTGDINFGVEVLCECFDKVKYKEKYTLND
LIIIDLFLTCAVVSKFNNRAFTKEVFQTICKTLISQNHKLTAEDLFWFNHVLLNCVFVGLCLNSEECLAEMLEVSRQTMV
STHDFHKMPLYFMYQWKYFITIDNDIKSAENAYQQSIMFSKMIDDKHLIKKLELEWQEDITGH

Nucleotide


Download         Length: 912 bp        

>NTDB_id=885364 QN329_RS02050 WP_000912100.1 348378..349289(-) (comR) [Streptococcus agalactiae strain HU36/21]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TATTTGATTTTAAGAATTCCAACTTATGCAGATGCTGAACGATTAAAATTAAGAGAATGTCAGTTTGATCATATTTTCGA
AGAATTCTATGATAATCTTCCAGAAGACGAGTGCTTAGCAATTGACAGTTTACAAGCTAAATTTGAAGTCTATCAAACAG
GAGACATTAATTTTGGTGTGGAGGTTTTATGCGAATGCTTTGATAAAGTAAAATATAAAGAAAAATATACTCTTAATGAT
TTGATTATCATAGATTTGTTTTTAACTTGTGCAGTTGTATCTAAATTTAACAATAGAGCATTTACTAAAGAAGTATTTCA
AACTATATGTAAAACTTTGATAAGTCAGAACCACAAACTTACAGCAGAAGATTTGTTTTGGTTTAATCATGTACTCCTGA
ATTGTGTATTTGTTGGACTTTGTTTAAATAGTGAAGAGTGTCTTGCAGAAATGTTAGAAGTTAGCCGACAAACGATGGTG
TCAACACATGATTTTCATAAAATGCCTTTATATTTTATGTACCAATGGAAATACTTCATTACAATTGACAATGATATAAA
GTCTGCAGAAAATGCTTACCAACAATCAATTATGTTTTCAAAAATGATTGATGACAAGCATCTAATTAAAAAATTAGAAT
TGGAGTGGCAAGAAGATATAACAGGACATTGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(10-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EEL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

52.667

99.01

0.521
  comR Streptococcus mutans UA159

44.816

98.68

0.442
  comR Streptococcus pyogenes MGAS8232

42.904

100

0.429
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

44.33

96.04

0.426