Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RMP66_RS05155 Genome accession   NZ_CP135094
Coordinates   1040134..1041513 (+) Length   459 a.a.
NCBI ID   WP_024394629.1    Uniprot ID   A0A0Z8PNG1
Organism   Streptococcus suis strain 1547095     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1035134..1046513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP66_RS05125 (RMP66_05125) pstA 1035605..1036492 (+) 888 WP_248022956.1 phosphate ABC transporter permease PstA -
  RMP66_RS05130 (RMP66_05130) pstB 1036517..1037320 (+) 804 WP_002937615.1 phosphate ABC transporter ATP-binding protein PstB -
  RMP66_RS05135 (RMP66_05135) pstB 1037332..1038090 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  RMP66_RS05140 (RMP66_05140) phoU 1038119..1038775 (+) 657 WP_024394630.1 phosphate signaling complex protein PhoU -
  RMP66_RS10790 - 1038941..1039276 (+) 336 Protein_974 hypothetical protein -
  RMP66_RS05150 (RMP66_05150) ciaR 1039470..1040141 (+) 672 WP_024385291.1 response regulator transcription factor Regulator
  RMP66_RS05155 (RMP66_05155) ciaH 1040134..1041513 (+) 1380 WP_024394629.1 cell wall metabolism sensor histidine kinase WalK Regulator
  RMP66_RS05160 (RMP66_05160) - 1041837..1043066 (+) 1230 WP_313910540.1 transglutaminase domain-containing protein -
  RMP66_RS05165 (RMP66_05165) rpsT 1043328..1043576 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  RMP66_RS05170 (RMP66_05170) coaA 1043635..1044555 (-) 921 WP_024381359.1 type I pantothenate kinase -
  RMP66_RS05175 (RMP66_05175) - 1044664..1045254 (+) 591 WP_009909951.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51923.64 Da        Isoelectric Point: 6.8882

>NTDB_id=885093 RMP66_RS05155 WP_024394629.1 1040134..1041513(+) (ciaH) [Streptococcus suis strain 1547095]
MPKRIRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDEDGTIQIAANIKDKLVCFTVIDNGLGISDT
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=885093 RMP66_RS05155 WP_024394629.1 1040134..1041513(+) (ciaH) [Streptococcus suis strain 1547095]
ATGCCTAAGCGAATCAGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGAAGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8PNG1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

49.451

99.129

0.49
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49