Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   RMP66_RS00825 Genome accession   NZ_CP135094
Coordinates   129540..130493 (+) Length   317 a.a.
NCBI ID   WP_024394706.1    Uniprot ID   A0A0Z8SW51
Organism   Streptococcus suis strain 1547095     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 124540..135493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP66_RS00785 (RMP66_00785) - 124803..125753 (-) 951 WP_024394700.1 S66 peptidase family protein -
  RMP66_RS00790 (RMP66_00790) comYA 125839..126789 (+) 951 WP_014637312.1 competence type IV pilus ATPase ComGA Machinery gene
  RMP66_RS00795 (RMP66_00795) comYB 126701..127738 (+) 1038 WP_043032925.1 competence type IV pilus assembly protein ComGB Machinery gene
  RMP66_RS00800 (RMP66_00800) comYC 127740..128021 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  RMP66_RS00805 (RMP66_00805) comGD 128002..128409 (+) 408 WP_024394702.1 competence type IV pilus minor pilin ComGD -
  RMP66_RS00810 (RMP66_00810) comYE 128381..128674 (+) 294 WP_024394703.1 competence type IV pilus minor pilin ComGE Machinery gene
  RMP66_RS00815 (RMP66_00815) comGF/cglF 128661..129095 (+) 435 WP_029750050.1 competence type IV pilus minor pilin ComGF Machinery gene
  RMP66_RS00820 (RMP66_00820) comGG 129073..129483 (+) 411 WP_024394705.1 competence type IV pilus minor pilin ComGG -
  RMP66_RS00825 (RMP66_00825) comYH 129540..130493 (+) 954 WP_024394706.1 class I SAM-dependent methyltransferase Machinery gene
  RMP66_RS00830 (RMP66_00830) - 130543..131730 (+) 1188 WP_014637319.1 acetate kinase -
  RMP66_RS00835 (RMP66_00835) - 132045..132596 (+) 552 WP_014636756.1 folate family ECF transporter S component -
  RMP66_RS00840 (RMP66_00840) - 132650..133906 (+) 1257 WP_172005964.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  RMP66_RS00845 (RMP66_00845) pepA 133951..135012 (-) 1062 WP_024394708.1 glutamyl aminopeptidase -
  RMP66_RS00850 (RMP66_00850) - 135159..135443 (+) 285 WP_012774909.1 DUF4651 domain-containing protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35744.84 Da        Isoelectric Point: 4.5053

>NTDB_id=885074 RMP66_RS00825 WP_024394706.1 129540..130493(+) (comYH) [Streptococcus suis strain 1547095]
MNFEKIEQAYDLLLENVQTIQNQLGTNIYDAMIEQNAAYVANQHETDLVVNNNKTLKQLDLTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLVPTQKVTVLEIGSGTGNLAQTILNASQKELDYLGIEVDDLLIDLSASIADVMQAD
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKNGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARSLTPFVYPLQSLQEPEAIQKFMLNFKNWKQENAI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=885074 RMP66_RS00825 WP_024394706.1 129540..130493(+) (comYH) [Streptococcus suis strain 1547095]
ATGAATTTTGAAAAGATCGAACAGGCTTACGACCTGCTATTAGAAAACGTACAGACTATCCAAAACCAGCTAGGTACCAA
TATCTATGATGCCATGATTGAGCAAAATGCTGCTTACGTAGCTAATCAGCATGAGACGGACCTTGTTGTCAATAATAACA
AGACCTTGAAACAACTAGATTTAACCAAGGAAGAATGGCGTCGTGCCTATCAATTCTTGCTCATCAAGGCCAATCAGACT
GAACCCATGCAGTATAATCACCAGTTCACACCAGACTCTATCGGATTTATCCTATCTTTTCTAGTAGACCAATTGGTGCC
GACTCAAAAGGTGACGGTTCTGGAAATTGGTTCGGGGACAGGCAATCTAGCTCAGACCATTCTCAACGCCAGCCAGAAAG
AATTGGATTACTTGGGGATCGAAGTGGACGACCTCTTGATTGATTTGTCGGCAAGTATTGCGGATGTCATGCAGGCAGAT
ATTTCTTTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAGGAAAGTCAAGTAATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGCTATCAGGTCGCCAGCCCAAATGAACATACCTACGCCCATCATTTACTCA
TGGAACAATCCCTCAAATATCTGGAAAAAAATGGTTTTGCGATTTTGTTGGCTCCAAATGATTTATTGACTAGTCCGCAA
AGCGATTTGCTGAAAGGTTGGTTACAGGAGCAAGCCAATATTGTTGCCATGATTGCCCTACCACCAAATCTCTTTGGGAA
GGCTGCTATGGCCAAGTCTATTTTTGTCTTGCAAAAGAAAGCTGCAAGATCATTGACGCCGTTTGTTTATCCCTTACAAA
GTCTTCAAGAACCAGAAGCTATTCAGAAGTTCATGCTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8SW51

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

60.759

99.685

0.606
  comYH Streptococcus mutans UA159

60.443

99.685

0.603