Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RMQ61_RS04635 Genome accession   NZ_CP135090
Coordinates   918067..919446 (+) Length   459 a.a.
NCBI ID   WP_044755070.1    Uniprot ID   -
Organism   Streptococcus suis strain ID48908     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 913067..924446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ61_RS04610 (RMQ61_04615) pstB 913597..914355 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  RMQ61_RS04615 (RMQ61_04620) phoU 914384..915040 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  RMQ61_RS04620 (RMQ61_04625) - 915242..916444 (-) 1203 WP_313921432.1 IS110 family transposase -
  RMQ61_RS04625 (RMQ61_04630) - 916829..917209 (+) 381 WP_136670726.1 hypothetical protein -
  RMQ61_RS04630 (RMQ61_04635) ciaR 917403..918074 (+) 672 WP_024400692.1 response regulator transcription factor Regulator
  RMQ61_RS04635 (RMQ61_04640) ciaH 918067..919446 (+) 1380 WP_044755070.1 cell wall metabolism sensor histidine kinase WalK Regulator
  RMQ61_RS04640 (RMQ61_04645) - 919771..921000 (+) 1230 WP_313926563.1 transglutaminase domain-containing protein -
  RMQ61_RS04645 (RMQ61_04650) rpsT 921263..921511 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  RMQ61_RS04650 (RMQ61_04655) coaA 921570..922490 (-) 921 WP_313921286.1 type I pantothenate kinase -
  RMQ61_RS04655 (RMQ61_04660) - 922599..923189 (+) 591 WP_024405804.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51933.65 Da        Isoelectric Point: 6.8879

>NTDB_id=884981 RMQ61_RS04635 WP_044755070.1 918067..919446(+) (ciaH) [Streptococcus suis strain ID48908]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQIAANIKDKLVCFTVIDNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=884981 RMQ61_RS04635 WP_044755070.1 918067..919446(+) (ciaH) [Streptococcus suis strain ID48908]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGTATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACTTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATCAGTTATCAAAAACAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGTATCGGATCTAGTTTGGAAGAAGTGCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTAGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGCC
GATAAAAAGAAAATCTTTGATCGATTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488