Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   RMQ63_RS07740 Genome accession   NZ_CP135063
Coordinates   1598525..1599817 (+) Length   430 a.a.
NCBI ID   WP_313680640.1    Uniprot ID   -
Organism   Streptococcus suis strain ID32563     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1593525..1604817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ63_RS07715 (RMQ63_07715) - 1594330..1594971 (+) 642 WP_024413700.1 response regulator transcription factor -
  RMQ63_RS07720 (RMQ63_07720) - 1595021..1596421 (+) 1401 WP_313680638.1 Cof-type HAD-IIB family hydrolase -
  RMQ63_RS07725 (RMQ63_07725) - 1596423..1596794 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  RMQ63_RS07730 (RMQ63_07730) cysK 1596820..1597746 (-) 927 WP_002937015.1 cysteine synthase A -
  RMQ63_RS07735 (RMQ63_07735) - 1597836..1598468 (-) 633 WP_313680639.1 YigZ family protein -
  RMQ63_RS07740 (RMQ63_07740) comFA/cflA 1598525..1599817 (+) 1293 WP_313680640.1 DEAD/DEAH box helicase Machinery gene
  RMQ63_RS07745 (RMQ63_07745) comFC/cflB 1599810..1600475 (+) 666 WP_313680641.1 ComF family protein Machinery gene
  RMQ63_RS07750 (RMQ63_07750) hpf 1600552..1601094 (+) 543 WP_313680642.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48867.42 Da        Isoelectric Point: 9.1612

>NTDB_id=884697 RMQ63_RS07740 WP_313680640.1 1598525..1599817(+) (comFA/cflA) [Streptococcus suis strain ID32563]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRAPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSIERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=884697 RMQ63_RS07740 WP_313680640.1 1598525..1599817(+) (comFA/cflA) [Streptococcus suis strain ID32563]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTGCGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAGCCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACGGGCAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTCCCCTTACTCATTTTTGTCCCAGAAATCTCTAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACGACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGAAGGAGTATAGAACGTCCGACTGGT
TTACTTCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae Rx1

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae D39

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae R6

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae TIGR4

66.125

100

0.663
  comFA/cflA Streptococcus mitis SK321

65.661

100

0.658
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.326

0.5
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363