Detailed information NTG0883759

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RNU01_RS04385
• Genome accession: NZ_CP134801
• Coordinates: 840834..841877 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA73_2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 835834..846877

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RNU01_RS04355	-	836200..836311 (+)	112	Protein_854	hypothetical protein	-
RNU01_RS04360	-	836340..836753 (+)	414	WP_001566709.1	hypothetical protein	-
RNU01_RS04365	-	837184..838170 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
RNU01_RS04370	map	838760..839518 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RNU01_RS04375	-	839735..840121 (+)	387	WP_001110179.1	hypothetical protein	-
RNU01_RS04380	liaF	840136..840837 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RNU01_RS04385	vraS	840834..841877 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RNU01_RS04390	vraR	841867..842496 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RNU01_RS04395	-	842608..843825 (-)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
RNU01_RS04400	-	844103..844378 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
RNU01_RS04405	-	844385..844849 (-)	465	WP_311904897.1	low molecular weight protein-tyrosine-phosphatase	-
RNU01_RS04410	-	844996..845196 (+)	201	WP_000180460.1	DUF1128 family protein	-
RNU01_RS04415	-	845199..846455 (+)	1257	WP_001789555.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=883759 RNU01_RS04385 WP_001017131.1 840834..841877(+) (vraS) [Staphylococcus aureus strain SA73_2]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=883759 RNU01_RS04385 WP_001017131.1 840834..841877(+) (vraS) [Staphylococcus aureus strain SA73_2]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1