Detailed information NTG0880401

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: RJW51_RS09725
• Genome accession: NZ_CP134491
• Coordinates: 1910465..1912702 (+)
• Length: 745 a.a.
• NCBI ID: WP_172089386.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain 1628469
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1900616..1909552	1910465..1912702	flank	913

Gene organization within MGE regions

Location: 1900616..1912702

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJW51_RS09665 (RJW51_09650)	-	1900616..1901476 (-)	861	WP_172016138.1	helix-turn-helix domain-containing protein	-
RJW51_RS09670 (RJW51_09655)	-	1901690..1901866 (+)	177	WP_172016139.1	hypothetical protein	-
RJW51_RS09675 (RJW51_09660)	-	1901921..1904140 (+)	2220	WP_172016140.1	peptide cleavage/export ABC transporter	-
RJW51_RS09680 (RJW51_09665)	-	1904133..1904600 (+)	468	WP_172016141.1	AraC family transcriptional regulator	-
RJW51_RS09685 (RJW51_09670)	-	1904597..1905997 (+)	1401	WP_172016142.1	HlyD family efflux transporter periplasmic adaptor subunit	-
RJW51_RS09690 (RJW51_09675)	-	1906143..1906517 (+)	375	WP_172016143.1	SPH_0224 family bacteriocin-like peptide	-
RJW51_RS09695 (RJW51_09680)	-	1906524..1906709 (+)	186	WP_397610462.1	hypothetical protein	-
RJW51_RS09700 (RJW51_09685)	-	1907581..1908186 (+)	606	WP_172036421.1	zinc metallopeptidase	-
RJW51_RS09705 (RJW51_09690)	-	1908228..1908806 (+)	579	Protein_1871	HlyD family efflux transporter periplasmic adaptor subunit	-
RJW51_RS09710 (RJW51_09695)	-	1908955..1909326 (+)	372	WP_172036422.1	hypothetical protein	-
RJW51_RS09715 (RJW51_09700)	-	1909331..1909552 (+)	222	WP_397610463.1	hypothetical protein	-
RJW51_RS09720 (RJW51_09705)	-	1909804..1910481 (+)	678	WP_172089387.1	helix-hairpin-helix domain-containing protein	-
RJW51_RS09725 (RJW51_09710)	comEC/celB	1910465..1912702 (+)	2238	WP_172089386.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84455.70 Da
• Isoelectric Point: 6.8517

>NTDB_id=880401 RJW51_RS09725 WP_172089386.1 1910465..1912702(+) (comEC/celB) [Streptococcus parasuis strain 1628469]
MSRLIRLPCQPIHYAVLAVLTYFAVHSFSLLTMSLLSLLLAVFRLRQGKVVFIKTLPLLALCGLFFGCQKIQWERTNLWA
PEQVTTVQVIPDTIDVNGDSLSFRGRAEGQVFQVFYKLASQEEQTYFQELTDLVQLEVDAEVCQPADQRNFNGFDYQAYL
KTQGIYRTVKISTINNILPIHSWNIFDWLSTWRRQALVYIKSHFPAPMSHYMTGLLLGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWLLLRLGLTMETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAATVFVCLLLM
PRFLLTAGGVLTFTYALLLTVFDFEELGQLKKIAVESLSISLGILPVLMSYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
ILLLSPFIKITWVNGFFILMEKIIVWVAELGIRPWILGKPTGLVFLLLLFCLFLLYDFHREKKWLLGLSLILALLFFITK
HPLENEVTVVDVGQGDSIFLRDIRGRTVLIDVGGRVNFATKEAWQERSRQANAERTLIPYLHSRGVDWIDSLVLTHTDAD
HVGDVLEVAKQIQIGKIYVSPGSLTVPDFVATLRKINVPVHVVKAGDQLPIFDSYLEVLYPNGIGDGGNNDSIVLYGRLL
KMNFLFTGDLEQGELDLITSYPQLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGENNRYQHPHQETLERFDRQNIQ
VYRTDLQGAIRFRGWKQWSIETVKE

Nucleotide

• Length: 2238 bp

>NTDB_id=880401 RJW51_RS09725 WP_172089386.1 1910465..1912702(+) (comEC/celB) [Streptococcus parasuis strain 1628469]
ATGTCACGGTTGATTAGACTCCCCTGTCAGCCCATTCACTATGCAGTATTGGCGGTGTTAACCTACTTTGCAGTCCACTC
TTTTTCCCTTTTGACAATGAGCCTGCTGAGTCTGTTACTAGCAGTCTTTAGGCTTCGGCAAGGAAAGGTGGTCTTCATCA
AAACGCTACCGCTTCTAGCCTTATGTGGTCTCTTCTTCGGATGTCAGAAGATACAATGGGAGCGGACAAATCTATGGGCT
CCAGAGCAAGTGACAACTGTGCAGGTTATTCCTGATACCATTGATGTCAACGGAGACAGTCTATCTTTTCGTGGTCGGGC
TGAAGGTCAAGTTTTTCAGGTTTTCTATAAACTTGCAAGTCAGGAAGAACAAACCTACTTTCAGGAGCTTACGGACTTGG
TGCAGTTAGAGGTAGATGCAGAAGTTTGCCAACCAGCAGATCAACGTAATTTCAATGGTTTTGATTATCAGGCTTATCTC
AAAACCCAGGGCATCTATCGGACAGTAAAAATAAGTACCATTAACAATATTCTCCCTATTCATTCTTGGAATATCTTTGA
CTGGTTGTCAACCTGGCGGAGGCAGGCTCTCGTTTATATCAAATCACATTTTCCTGCTCCCATGAGCCACTATATGACTG
GATTACTATTGGGAGAGTTAGATAGTGACTTTGACCAAATGAGTGACCTCTATTCTAGTCTAGGGATCATTCATCTTTTT
GCCCTGTCTGGGATGCAGGTTGGTTTTTTCATTGACAAATTTCGCTGGCTTTTATTGCGTTTGGGTTTAACAATGGAAAC
TGTCGATAAGCTTCAAATTCCGTTTTCTCTTGTTTATGCAGGATTAACAGGATTTTCAGTATCAGTCGTGCGGTCCTTGG
TCCAGAAAATTCTTGGTAATCTCGGGCTACGAAAATTGGATAATTTTGCAGCAACTGTCTTTGTTTGTCTCTTGCTTATG
CCACGTTTTCTTCTGACAGCAGGAGGTGTGCTGACATTTACCTATGCTTTGTTATTGACAGTCTTTGATTTTGAAGAGCT
AGGGCAGCTAAAGAAGATAGCAGTGGAGAGTCTGAGTATTTCTCTTGGAATTTTACCGGTCTTGATGTCCTATTTTTTTG
CCTTTCAGCCCTTATCTATCCTTTTAACGTTTGTTTTTTCCTTTGTTTTTGATGTGTTGTTGTTACCTGGGCTATCTGTC
ATTCTTTTACTATCGCCCTTCATTAAAATTACGTGGGTCAACGGATTCTTTATCCTTATGGAAAAGATTATTGTATGGGT
GGCAGAATTGGGGATTCGCCCTTGGATTTTAGGAAAACCTACGGGCCTTGTCTTTTTGCTCTTACTGTTCTGCCTTTTCT
TGCTTTATGATTTTCACAGAGAGAAGAAATGGCTCCTTGGATTGAGTCTGATCCTTGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAATGAGGTGACGGTGGTAGACGTAGGGCAGGGGGATAGTATCTTTTTGCGGGACATTCGGGGGCGGAC
GGTTCTGATTGATGTGGGTGGTCGGGTTAACTTTGCTACAAAGGAAGCGTGGCAGGAGCGATCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGAGGTGTGGATTGGATTGATAGCCTAGTGCTGACTCACACCGATGCAGAT
CATGTGGGTGATGTGCTAGAAGTGGCTAAGCAGATTCAAATAGGTAAGATTTACGTTTCTCCAGGTAGTTTAACTGTTCC
AGATTTTGTTGCGACTTTGAGGAAAATCAATGTCCCTGTTCATGTTGTAAAAGCTGGGGATCAATTGCCCATTTTTGATT
CCTATCTAGAAGTTCTATATCCCAATGGAATCGGAGATGGAGGCAATAATGACTCAATTGTACTCTATGGTCGTTTGTTA
AAAATGAATTTCCTCTTTACCGGTGACTTGGAGCAAGGGGAATTAGATTTAATCACTTCTTATCCGCAGTTACCAGTCGA
TGTGCTGAAAGCAGGTCACCATGGCTCCAAGGGCTCTTCATATCCAGAATTTTTAGACCATATTGGAGCAAAAATTGCTC
TGATTTCTGCTGGTGAAAATAATCGCTATCAACATCCGCATCAGGAAACTCTGGAACGTTTCGACAGGCAAAATATACAG
GTTTACCGAACGGATCTGCAAGGAGCAATCCGTTTCCGAGGTTGGAAACAGTGGAGTATTGAAACGGTAAAAGAGTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-698)

• Domain of unknown function (DUF4131) (DUF4131) (29-176)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.815	100	0.54
comEC/celB	Streptococcus mitis NCTC 12261	52.965	99.597	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	52.086	99.732	0.519
comEC/celB	Streptococcus pneumoniae Rx1	51.548	99.732	0.514
comEC/celB	Streptococcus pneumoniae D39	51.548	99.732	0.514
comEC/celB	Streptococcus pneumoniae R6	51.548	99.732	0.514
comEC	Lactococcus lactis subsp. cremoris KW2	47.931	100	0.482