Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RJW53_RS06615 Genome accession   NZ_CP134488
Coordinates   1280887..1282266 (-) Length   459 a.a.
NCBI ID   WP_024381361.1    Uniprot ID   A0A075SID2
Organism   Streptococcus suis strain NLS50     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1275887..1287266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS06595 (RJW53_06595) - 1277147..1277737 (-) 591 WP_023369994.1 class I SAM-dependent methyltransferase -
  RJW53_RS06600 (RJW53_06600) coaA 1277845..1278765 (+) 921 WP_002935283.1 type I pantothenate kinase -
  RJW53_RS06605 (RJW53_06605) rpsT 1278824..1279072 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  RJW53_RS06610 (RJW53_06610) - 1279334..1280563 (-) 1230 WP_023369936.1 transglutaminase domain-containing protein -
  RJW53_RS06615 (RJW53_06615) ciaH 1280887..1282266 (-) 1380 WP_024381361.1 cell wall metabolism sensor histidine kinase WalK Regulator
  RJW53_RS06620 (RJW53_06620) ciaR 1282259..1282930 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  RJW53_RS06625 (RJW53_06625) - 1283124..1283504 (-) 381 WP_023369940.1 hypothetical protein -
  RJW53_RS06630 (RJW53_06630) phoU 1283670..1284326 (-) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  RJW53_RS06635 (RJW53_06635) pstB 1284355..1285113 (-) 759 WP_074389058.1 phosphate ABC transporter ATP-binding protein PstB -
  RJW53_RS06640 (RJW53_06640) pstB 1285125..1285928 (-) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  RJW53_RS06645 (RJW53_06645) pstA 1285953..1286840 (-) 888 WP_002937616.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51961.70 Da        Isoelectric Point: 6.8882

>NTDB_id=880321 RJW53_RS06615 WP_024381361.1 1280887..1282266(-) (ciaH) [Streptococcus suis strain NLS50]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDEDGTIQIAANIKDKLVCFTVIDNGLGISDT
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=880321 RJW53_RS06615 WP_024381361.1 1280887..1282266(-) (ciaH) [Streptococcus suis strain NLS50]
ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGAAGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SID2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae D39

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae R6

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.345

99.782

0.492
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488