Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   RJW53_RS00340 Genome accession   NZ_CP134488
Coordinates   57043..57942 (+) Length   299 a.a.
NCBI ID   WP_012774888.1    Uniprot ID   A0A116VRL0
Organism   Streptococcus suis strain NLS50     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 55476..59506 57043..57942 within 0


Gene organization within MGE regions


Location: 55476..59506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS00335 (RJW53_00335) - 55476..56678 (-) 1203 WP_074389402.1 IS110 family transposase -
  RJW53_RS00340 (RJW53_00340) comR 57043..57942 (+) 900 WP_012774888.1 helix-turn-helix domain-containing protein Regulator
  RJW53_RS00345 (RJW53_00345) - 58568..59506 (-) 939 WP_011921674.1 IS4 family transposase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35405.30 Da        Isoelectric Point: 4.6492

>NTDB_id=880294 RJW53_RS00340 WP_012774888.1 57043..57942(+) (comR) [Streptococcus suis strain NLS50]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=880294 RJW53_RS00340 WP_012774888.1 57043..57942(+) (comR) [Streptococcus suis strain NLS50]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGTG
TAAATATATTAGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
AGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116VRL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

100

100

1
  comR Streptococcus suis 05ZYH33

100

100

1
  comR Streptococcus suis D9

62.126

100

0.625
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371