Detailed information
Bioinformatically predicted
Overview
| Name | comR | Type | Regulator |
| Locus tag | RJW49_RS00320 | Genome accession | NZ_CP134477 |
| Coordinates | 54980..55879 (+) | Length | 299 a.a. |
| NCBI ID | WP_044678694.1 | Uniprot ID | A0A0Z8MQY0 |
| Organism | Streptococcus suis strain NLS40 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 44672..54030 | 54980..55879 | flank | 950 |
| IScluster/Tn | 52527..58999 | 54980..55879 | within | 0 |
Gene organization within MGE regions
Location: 44672..58999
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RJW49_RS00275 (RJW49_00275) | purD | 44672..45937 (+) | 1266 | WP_074393607.1 | phosphoribosylamine--glycine ligase | - |
| RJW49_RS00280 (RJW49_00280) | - | 45927..46373 (+) | 447 | WP_014735223.1 | DUF523 domain-containing protein | - |
| RJW49_RS00285 (RJW49_00285) | purE | 46370..46858 (+) | 489 | WP_014735224.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| RJW49_RS00290 (RJW49_00290) | purK | 46845..47939 (+) | 1095 | WP_014735225.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
| RJW49_RS00295 (RJW49_00295) | - | 47954..50476 (+) | 2523 | WP_014735226.1 | DEAD/DEAH box helicase | - |
| RJW49_RS00300 (RJW49_00300) | purB | 50871..52163 (+) | 1293 | WP_014735227.1 | adenylosuccinate lyase | - |
| RJW49_RS00305 (RJW49_00305) | tnpA | 52354..52867 (+) | 514 | Protein_40 | IS200/IS605 family transposase | - |
| RJW49_RS00310 (RJW49_00310) | ruvB | 53029..54030 (+) | 1002 | WP_014735241.1 | Holliday junction branch migration DNA helicase RuvB | - |
| RJW49_RS00315 (RJW49_00315) | - | 54098..54733 (+) | 636 | WP_014735242.1 | HAD-IA family hydrolase | - |
| RJW49_RS00320 (RJW49_00320) | comR | 54980..55879 (+) | 900 | WP_044678694.1 | helix-turn-helix domain-containing protein | Regulator |
| RJW49_RS00325 (RJW49_00325) | - | 56305..57507 (+) | 1203 | WP_079759536.1 | IS110 family transposase | - |
| RJW49_RS00330 (RJW49_00330) | - | 58062..58999 (-) | 938 | Protein_45 | IS4 family transposase | - |
Sequence
Protein
Download Length: 299 a.a. Molecular weight: 35435.33 Da Isoelectric Point: 4.6492
>NTDB_id=880189 RJW49_RS00320 WP_044678694.1 54980..55879(+) (comR) [Streptococcus suis strain NLS40]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ
Nucleotide
Download Length: 900 bp
>NTDB_id=880189 RJW49_RS00320 WP_044678694.1 54980..55879(+) (comR) [Streptococcus suis strain NLS40]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comR | Streptococcus suis P1/7 |
99.666 |
100 |
0.997 |
| comR | Streptococcus suis 05ZYH33 |
99.666 |
100 |
0.997 |
| comR | Streptococcus suis D9 |
61.794 |
100 |
0.622 |
| comR | Streptococcus mutans UA159 |
43.813 |
100 |
0.438 |
| comR | Streptococcus pyogenes MGAS315 |
37.374 |
99.331 |
0.371 |