Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   RJW55_RS07585 Genome accession   NZ_CP134473
Coordinates   1617788..1620025 (-) Length   745 a.a.
NCBI ID   WP_043026930.1    Uniprot ID   -
Organism   Streptococcus suis strain TMW_SS028     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1612788..1625025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW55_RS07585 (RJW55_07585) comEC/celB 1617788..1620025 (-) 2238 WP_043026930.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  RJW55_RS07590 (RJW55_07590) - 1620009..1620671 (-) 663 WP_043026931.1 helix-hairpin-helix domain-containing protein -
  RJW55_RS07595 (RJW55_07595) - 1620738..1621484 (-) 747 WP_043026932.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  RJW55_RS07600 (RJW55_07600) - 1621633..1623078 (+) 1446 WP_043026933.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  RJW55_RS07605 (RJW55_07605) - 1623544..1624329 (+) 786 WP_014636900.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84439.31 Da        Isoelectric Point: 7.0168

>NTDB_id=880173 RJW55_RS07585 WP_043026930.1 1617788..1620025(-) (comEC/celB) [Streptococcus suis strain TMW_SS028]
MSRSIKLPCQPIHLAVLAVAAYFAVHSFSLLTMGLLSFLLVVFGFRQGKTVFLKTLPLLALFSLFFGYQKVQWERADQLA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQTYFQKLTDLVQLEVEAEISLPTGQRNFKGFDYQAYL
KTQGIYRTVKISAIKKIVLVQSWNIFDWLSSWRRKALVYVKTNFPAPMSHYMTGLLFGELDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSLFYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVSVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLEQVKKAAVESLSISLGILPILMTYFYAFQPLSILLTFVFSFIFDVLLLPGLSV
IFLLSPVVKMTWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
YPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEEWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVAVGDRLPIFDSYLEVLYPSGTGDGGNNDSVVLYGRLL
ETNFLFTGDLEQGELDLIKTYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDNRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=880173 RJW55_RS07585 WP_043026930.1 1617788..1620025(-) (comEC/celB) [Streptococcus suis strain TMW_SS028]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATCCATCTGGCAGTCTTGGCGGTGGCGGCCTACTTTGCAGTCCACTC
TTTTTCCCTGTTGACAATGGGCCTGTTGAGTTTCTTACTAGTTGTCTTTGGGTTTCGGCAAGGTAAGACAGTTTTTCTCA
AAACGCTACCGCTTCTAGCCCTGTTCAGTCTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTTAGCC
CCAGAGCAAGTCACAACTGTGCAGGTCATTCCAGATACGATTGAAGTAAACGGGGACAGCTTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTGTTCTACAAATTAGCTAGTCAGGAGGAGCAAACTTATTTTCAAAAGTTGACAGATTTGG
TCCAGCTAGAAGTGGAAGCAGAGATTAGCCTGCCAACTGGTCAACGGAATTTCAAGGGCTTTGACTACCAAGCCTATCTG
AAAACGCAGGGAATTTATCGGACAGTTAAGATTTCTGCGATAAAGAAGATTGTCCTTGTCCAGTCGTGGAATATTTTTGA
CTGGTTATCAAGTTGGCGGAGGAAAGCCTTGGTCTATGTCAAAACCAATTTTCCAGCTCCCATGAGCCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGAGTTTGACCAGATGAGTGACCTCTATTCCAGTCTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAGC
TGTAGATAAGTTGCAGATTCCCTTTTCACTTTTTTATGCTGGTTTGACAGGCTTTTCCGTGTCGGTGGTGCGGTCCTTGG
TACAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAACTTTGCGGTGTCGGTCTTTGTCTGTCTGCTGATTCTG
CCCCGATTTCTGCTGACAGCTGGCGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAAGACTT
GGAGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGAATTTTGCCGATTCTCATGACCTATTTCTATG
CCTTCCAGCCCTTGTCTATTCTCTTGACCTTTGTCTTTTCCTTTATTTTTGATGTCCTGCTCTTGCCAGGTTTGTCGGTC
ATTTTTCTTTTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGGATTTTTTGTCTTTATGGAGAAGATTATTGTCTGGGT
GGCTGACTTGGGTTTCAGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
TACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGTATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGTGGTCGGGTTGATTTTGCGGCTAAGGAGGAGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCACAGTCGGGGCGTGGATAGGATTGATAGTCTAGTGCTGACCCACACCGACACAGAC
CATGTGGGCGATGTGCTAGAAGTGGCTAAGCAGGTACAAATTGGTCGAATTTACGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCGACTTTGAAAGAAATCAATGTCCCTGTTCATGTGGTGGCGGTAGGCGACCGCTTGCCGATTTTTGACT
CTTACCTAGAAGTCCTCTATCCAAGTGGAACGGGCGACGGTGGCAATAATGACTCTGTTGTTCTTTACGGTCGCTTGTTG
GAAACCAATTTTCTCTTTACAGGGGACTTGGAGCAAGGGGAGCTGGACTTGATCAAAACCTATCCCAATCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCTAAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAATAACCGCTACAAGCATCCCCATCAAGAAACCTTGGAACGATTTGACAATCGGAATATCCAA
GTCTATCGAACTGATCAGCAGGGCGCCATTCGCTTTCGAGGTTGGAGGGAGTGGCGAATTGAAACGGTGAGGGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(28-176)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

55.21

99.195

0.548
  comEC/celB Streptococcus mitis NCTC 12261

53.867

98.926

0.533
  comEC/celB Streptococcus pneumoniae TIGR4

53.333

98.658

0.526
  comEC/celB Streptococcus pneumoniae Rx1

52.789

98.658

0.521
  comEC/celB Streptococcus pneumoniae D39

52.789

98.658

0.521
  comEC/celB Streptococcus pneumoniae R6

52.789

98.658

0.521
  comEC Lactococcus lactis subsp. cremoris KW2

48.594

100

0.487