Detailed information NTG0880071

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RIU93_RS07545
• Genome accession: NZ_CP134464
• Coordinates: 1525190..1526233 (-)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain 2023.05
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1520190..1531233

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIU93_RS07515 (RIU93_07515)	-	1520688..1521929 (-)	1242	WP_058710066.1	aminopeptidase	-
RIU93_RS07520 (RIU93_07520)	-	1521942..1522145 (-)	204	WP_002466135.1	DUF1128 domain-containing protein	-
RIU93_RS07525 (RIU93_07525)	-	1522292..1522756 (+)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
RIU93_RS07530 (RIU93_07530)	-	1522763..1523047 (+)	285	WP_002466132.1	YtxH domain-containing protein	-
RIU93_RS07535 (RIU93_07535)	-	1523277..1524512 (+)	1236	WP_015364859.1	YihY/virulence factor BrkB family protein	-
RIU93_RS07540 (RIU93_07540)	vraR	1524571..1525200 (-)	630	WP_058710065.1	response regulator transcription factor	Regulator
RIU93_RS07545 (RIU93_07545)	vraS	1525190..1526233 (-)	1044	WP_002466111.1	sensor histidine kinase	Regulator
RIU93_RS07550 (RIU93_07550)	liaF	1526230..1526931 (-)	702	WP_015364858.1	cell wall-active antibiotics response protein LiaF	-
RIU93_RS07555 (RIU93_07555)	-	1526946..1527332 (-)	387	WP_002466133.1	DUF2543 family protein	-
RIU93_RS07560 (RIU93_07560)	map	1527476..1528231 (-)	756	WP_002466104.1	type I methionyl aminopeptidase	-
RIU93_RS07565 (RIU93_07565)	-	1528398..1529384 (+)	987	WP_015364857.1	aromatic acid exporter family protein	-
RIU93_RS07570 (RIU93_07570)	-	1529452..1530177 (-)	726	WP_023373124.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=880071 RIU93_RS07545 WP_002466111.1 1525190..1526233(-) (vraS) [Staphylococcus warneri strain 2023.05]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=880071 RIU93_RS07545 WP_002466111.1 1525190..1526233(-) (vraS) [Staphylococcus warneri strain 2023.05]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTTCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGCAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948