Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RIN70_RS04275 Genome accession   NZ_CP134147
Coordinates   833063..834424 (+) Length   453 a.a.
NCBI ID   WP_313790710.1    Uniprot ID   -
Organism   Streptococcus parasanguinis strain 30.8.10     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 828063..839424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIN70_RS04255 (RIN70_04255) - 828385..830928 (+) 2544 WP_195623089.1 M1 family metallopeptidase -
  RIN70_RS04260 (RIN70_04260) - 830985..831518 (-) 534 WP_003006609.1 biotin transporter BioY -
  RIN70_RS04265 (RIN70_04265) - 831724..832263 (+) 540 WP_313790709.1 hypothetical protein -
  RIN70_RS04270 (RIN70_04270) ciaR 832399..833079 (+) 681 WP_003003305.1 response regulator transcription factor Regulator
  RIN70_RS04275 (RIN70_04275) ciaH 833063..834424 (+) 1362 WP_313790710.1 HAMP domain-containing sensor histidine kinase Regulator
  RIN70_RS04280 (RIN70_04280) - 834454..834834 (+) 381 WP_003006623.1 VOC family protein -
  RIN70_RS04285 (RIN70_04285) - 835093..836475 (+) 1383 WP_070666109.1 polysaccharide deacetylase family protein -
  RIN70_RS04290 (RIN70_04290) - 836518..837603 (-) 1086 WP_070589290.1 DEAD/DEAH box helicase -
  RIN70_RS04295 (RIN70_04295) - 837600..838580 (-) 981 WP_313790711.1 Gfo/Idh/MocA family oxidoreductase -
  RIN70_RS04300 (RIN70_04300) - 838708..839418 (+) 711 WP_049490916.1 glycosyltransferase family 2 protein -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 52016.36 Da        Isoelectric Point: 6.2114

>NTDB_id=878872 RIN70_RS04275 WP_313790710.1 833063..834424(+) (ciaH) [Streptococcus parasanguinis strain 30.8.10]
MLTRIKKTVGEDDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTTVDENLRTLSQDPYSLVAIAYRDQRQSTNKDDDND
HGMMLPDHDKSEPKGDVTSNTTVVLLNKKYENLTTGNGFLNFKTVTFGRKLLNKVSQLQITNSYGKKESYRAYMAELSLS
DDEDESNIKYAVIMTNISQLEQTSEEHESQIALVMICFWGISLFASLFLARLSVKPLLESMQKQKSFVENASHELRTPLA
VLQNRLETLFRKPEATIMESSESIASSLDEVRNMKLLTTNLLNIARRDDGLKPEMEDIEPSFFDQTFSNFEIIAEENDKI
FRGDNQVDKVICSDRTLLKQLMTILYDNALKYTDEDGEIQFEVQLKDKNLLLRVLDNGPGIRDEDKKRIFDRFYRVDKAR
TRQKGGFGLGLSLAKQIVEAFKGTIQVKDNKPKGTIFEVKLSIKTESRKKNRS

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=878872 RIN70_RS04275 WP_313790710.1 833063..834424(+) (ciaH) [Streptococcus parasanguinis strain 30.8.10]
ATGCTAACAAGGATTAAGAAAACCGTCGGAGAAGATGATTTTTCCTACTTCATCCGATATTTTGGACTCTTTACTTTGAT
ATTCTCGGCCATGACCTTGATTATCATTCAGGTCATGCGCTCGAGTCTCTATACAACCGTCGATGAGAACCTCAGGACTC
TCAGTCAGGATCCTTACTCACTTGTAGCGATTGCTTATCGAGATCAGCGACAATCAACTAATAAAGATGATGATAACGAT
CATGGGATGATGTTACCTGACCATGACAAATCAGAACCTAAAGGAGATGTCACATCCAATACCACTGTTGTTTTGCTCAA
TAAAAAATATGAAAACTTGACAACTGGTAACGGGTTTCTAAACTTTAAAACAGTGACGTTTGGCCGAAAACTTCTCAATA
AGGTTTCTCAGCTTCAAATTACCAATAGCTATGGGAAAAAAGAAAGTTATCGGGCCTATATGGCAGAGTTGAGTCTATCT
GATGATGAAGATGAAAGTAATATCAAGTATGCGGTCATCATGACCAATATTAGTCAGCTAGAGCAGACCAGTGAGGAACA
TGAAAGCCAGATCGCTCTTGTCATGATTTGCTTCTGGGGAATCTCCTTGTTTGCGAGTCTCTTCCTTGCCCGTCTTAGCG
TTAAGCCGCTGCTTGAGAGTATGCAAAAGCAAAAGTCTTTTGTAGAAAATGCTTCTCATGAGTTGCGGACGCCTCTAGCA
GTCTTACAAAATCGCCTCGAAACGCTTTTTAGAAAGCCTGAAGCGACCATTATGGAATCGAGCGAGAGCATTGCATCTAG
CTTAGATGAAGTTCGAAATATGAAGCTCTTGACCACCAACCTTCTCAATATCGCCCGAAGAGATGATGGCTTGAAGCCAG
AGATGGAAGACATCGAACCAAGCTTTTTCGATCAGACCTTCTCGAATTTTGAGATCATTGCGGAAGAAAATGACAAAATC
TTCCGAGGAGACAATCAGGTGGACAAAGTCATTTGTTCTGATAGAACGCTCCTCAAGCAATTGATGACCATTCTCTATGA
TAATGCCTTGAAATATACCGATGAAGATGGCGAGATCCAGTTTGAAGTTCAATTGAAGGACAAAAATCTACTTTTGAGGG
TGCTGGATAATGGTCCAGGGATTCGAGATGAGGATAAGAAACGGATCTTTGATCGTTTTTACCGGGTCGACAAGGCCAGA
ACCCGTCAAAAAGGTGGATTTGGTTTGGGGTTATCCCTCGCTAAGCAGATTGTAGAAGCCTTCAAAGGGACCATTCAAGT
CAAAGATAATAAACCCAAAGGGACCATCTTTGAAGTGAAATTATCCATTAAGACGGAAAGTCGTAAAAAAAATCGTTCAT
AA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(225-290)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(334-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

61.111

99.338

0.607
  ciaH Streptococcus pneumoniae D39

61.111

99.338

0.607
  ciaH Streptococcus pneumoniae R6

61.111

99.338

0.607
  ciaH Streptococcus pneumoniae TIGR4

61.111

99.338

0.607
  ciaH Streptococcus mutans UA159

50.34

97.351

0.49