Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   RG494_RS07815 Genome accession   NZ_CP134046
Coordinates   1680839..1682173 (+) Length   444 a.a.
NCBI ID   WP_241951591.1    Uniprot ID   -
Organism   Pasteurella multocida strain AKS2022-HT5     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1675839..1687173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG494_RS07790 - 1675915..1678476 (-) 2562 WP_241951586.1 penicillin-binding protein 1A -
  RG494_RS07795 - 1678612..1679385 (+) 774 WP_241951587.1 competence protein ComA -
  RG494_RS07800 - 1679425..1679940 (+) 516 WP_241951588.1 competence protein ComB -
  RG494_RS07805 - 1679940..1680464 (+) 525 WP_310549681.1 ATPase -
  RG494_RS07810 - 1680467..1680829 (+) 363 WP_241951590.1 pilus assembly protein PilP -
  RG494_RS07815 comE 1680839..1682173 (+) 1335 WP_241951591.1 type IV pilus secretin PilQ Machinery gene
  RG494_RS07820 aroK 1682356..1682883 (+) 528 WP_005717623.1 shikimate kinase AroK -
  RG494_RS07825 aroB 1682900..1683988 (+) 1089 WP_115173789.1 3-dehydroquinate synthase -
  RG494_RS07830 - 1683992..1684897 (+) 906 WP_241951592.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  RG494_RS07835 - 1684944..1685249 (-) 306 WP_241951593.1 DciA family protein -
  RG494_RS07840 secM 1685342..1685653 (+) 312 WP_374762034.1 secA translation cis-regulator SecM -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 49285.64 Da        Isoelectric Point: 7.3925

>NTDB_id=878303 RG494_RS07815 WP_241951591.1 1680839..1682173(+) (comE) [Pasteurella multocida strain AKS2022-HT5]
MWRAFRKISFVYFLCGVAYVGSSQAQDAEHFYLRLKQAPLVEMLQYLALQQHQDLLIDDHLEGTLSLQMKKTTFEKCLQS
IARMKQLELHQEGKSYYLTSPSGVAANDTHHPTSLMTSSIKLHFAKAAEVVKSLTSGQGSLLSVGGSLSFDERTNLLLIQ
DEPQSIQRIKALVAEMDKPIEQIAIEARIVTMTDESLQELGVRWGLFQATEQAHTIAGSLAANGFSNIENQLNVNFSTNS
APVGSIALQLAKINGRLLDLELTALEREKHIEIIASPRLLTTNKKSASIKQGTEIPYVMKRGKDKSESVEFREAVLGLDV
TPHISKDNTILLDLLITQNTLGAPVVYDKGEIVSIDKQEINTQVVAQDGETIVLGGVFHDTMTKGVNKVPLLGDLPLLKH
VFSQETERHQKRELVIFVTPHIIKPTQSSPEQKTTRVKKSAKSR

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=878303 RG494_RS07815 WP_241951591.1 1680839..1682173(+) (comE) [Pasteurella multocida strain AKS2022-HT5]
ATGTGGCGAGCATTCAGAAAAATATCTTTTGTGTACTTTTTATGTGGAGTTGCTTATGTTGGAAGTAGTCAAGCACAAGA
CGCAGAACATTTTTATTTACGTTTAAAACAAGCGCCTTTAGTCGAAATGTTACAGTATTTAGCATTACAACAACATCAGG
ATTTGTTAATCGATGATCATTTAGAGGGCACATTATCATTACAGATGAAAAAGACAACCTTTGAGAAATGTTTACAGTCG
ATTGCAAGAATGAAACAACTTGAGTTACATCAAGAAGGGAAATCCTATTATTTAACTTCCCCTTCAGGTGTTGCAGCAAA
CGATACTCATCATCCTACGTCATTGATGACATCTTCAATAAAATTGCATTTTGCCAAAGCTGCAGAGGTAGTGAAATCTT
TAACTTCAGGGCAGGGAAGTTTACTTTCTGTCGGGGGGAGTTTGAGTTTTGATGAGCGGACTAATTTACTGCTGATTCAG
GATGAACCGCAATCGATACAGCGTATTAAAGCATTAGTAGCAGAAATGGATAAACCCATTGAACAAATTGCGATCGAAGC
CAGAATTGTGACGATGACAGACGAAAGTTTGCAGGAACTTGGCGTAAGATGGGGGCTATTTCAAGCAACAGAACAGGCAC
ATACTATTGCTGGGAGTTTAGCTGCAAACGGCTTTTCAAATATAGAAAACCAATTAAATGTGAATTTCTCGACCAATAGT
GCACCAGTTGGTTCCATCGCCCTACAGTTGGCGAAAATAAATGGTCGATTATTAGACTTGGAATTAACTGCCTTGGAACG
AGAAAAGCATATTGAGATTATTGCGAGTCCTCGTTTATTAACAACGAATAAAAAAAGTGCCAGTATTAAACAAGGGACGG
AAATTCCTTATGTGATGAAACGGGGAAAAGATAAAAGCGAATCGGTGGAATTTCGAGAAGCTGTATTAGGTTTAGATGTG
ACACCGCATATCTCAAAAGACAACACGATTTTATTAGATTTATTGATTACACAAAATACATTAGGTGCACCGGTAGTGTA
TGATAAAGGCGAAATTGTTTCGATCGATAAACAGGAAATCAATACTCAAGTCGTCGCGCAAGATGGTGAAACCATCGTTT
TAGGCGGGGTGTTTCATGATACGATGACAAAGGGAGTCAATAAAGTACCACTACTAGGGGATTTGCCTTTGCTTAAACAT
GTGTTTAGCCAGGAAACTGAACGTCATCAAAAGCGGGAATTAGTGATTTTTGTCACGCCTCATATTATCAAACCGACCCA
AAGTTCGCCTGAACAAAAAACAACGAGAGTTAAAAAATCTGCAAAATCAAGGTGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(264-424)

Bacterial type II/III secretion system short domain (Secretin_N)

(119-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

62.125

97.523

0.606
  comE Haemophilus influenzae 86-028NP

61.432

97.523

0.599
  comE Glaesserella parasuis strain SC1401

48.611

97.297

0.473
  pilQ Vibrio campbellii strain DS40M4

39.524

94.595

0.374
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

39.806

92.793

0.369
  pilQ Vibrio cholerae strain A1552

39.806

92.793

0.369