Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RDV49_RS08500 Genome accession   NZ_CP133988
Coordinates   1762953..1764314 (-) Length   453 a.a.
NCBI ID   WP_003006620.1    Uniprot ID   A0AAX4AWP8
Organism   Streptococcus parasanguinis strain B-1756     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1757953..1769314
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS08480 (RDV49_08480) - 1758945..1759925 (+) 981 WP_003006633.1 Gfo/Idh/MocA family protein -
  RDV49_RS08485 (RDV49_08485) - 1759922..1761007 (+) 1086 WP_003006630.1 DEAD/DEAH box helicase -
  RDV49_RS08490 (RDV49_08490) - 1761050..1762432 (-) 1383 WP_003006627.1 polysaccharide deacetylase family protein -
  RDV49_RS08495 (RDV49_08495) - 1762543..1762923 (-) 381 WP_003006623.1 VOC family protein -
  RDV49_RS08500 (RDV49_08500) ciaH 1762953..1764314 (-) 1362 WP_003006620.1 cell wall metabolism sensor histidine kinase WalK Regulator
  RDV49_RS08505 (RDV49_08505) ciaR 1764298..1764978 (-) 681 WP_037607818.1 response regulator transcription factor Regulator
  RDV49_RS08510 (RDV49_08510) - 1765114..1765653 (-) 540 WP_003006614.1 hypothetical protein -
  RDV49_RS08515 (RDV49_08515) - 1765860..1766393 (+) 534 WP_003006609.1 biotin transporter BioY -
  RDV49_RS08520 (RDV49_08520) - 1766450..1768993 (-) 2544 WP_037607815.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 51890.25 Da        Isoelectric Point: 6.5326

>NTDB_id=878171 RDV49_RS08500 WP_003006620.1 1762953..1764314(-) (ciaH) [Streptococcus parasanguinis strain B-1756]
MLTRIKKTVGEDDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTTVDENLKTLSQDPYSLVAIAYRDQRQSNTKGDDND
HEMMIPDHDKSEPKGDVTSNTTVVLLNKKYENLTTGNGFLNFKTVTFGRKLLNKVSQLQITNSYGKKESYRAYMAELSLS
DDESDSDIKYAVVMTNISQLEQTSEEHESQIALIMICFWGISLFASLFLARLSVKPLLESMQKQKAFVENASHELRTPLA
VLQNRLETLFRKPEATIMESSENIASSLDEVRNMKLLTTNLLNIARRDDGLKPEMEDIEPSFFDQSFSNFEIIAEENGKI
FRGDNQVDKVICSDRTLLKQLMTILYDNALKYTDEDGEIQFEVQLKDKNLLLRVLDNGSGIRDEDKKRIFDRFYRVDKAR
TRQKGGFGLGLSLAKQIVEAFKGTIQVKDNKPKGTIFEVKLSIKTESRKKNRS

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=878171 RDV49_RS08500 WP_003006620.1 1762953..1764314(-) (ciaH) [Streptococcus parasanguinis strain B-1756]
ATGCTAACCAGAATTAAGAAAACCGTCGGAGAAGATGATTTTTCCTACTTCATCCGATATTTTGGGCTCTTTACTTTGAT
ATTCTCAGCCATGACCTTGATTATCATTCAGGTCATGCGCTCGAGTCTTTATACAACTGTTGATGAGAACCTCAAGACTC
TCAGTCAGGATCCCTACTCGCTTGTAGCGATTGCTTATCGAGACCAGCGACAGTCAAATACCAAAGGAGATGATAATGAT
CATGAGATGATGATCCCAGATCATGATAAATCAGAACCTAAAGGGGATGTCACATCCAATACCACTGTTGTTTTGCTTAA
TAAAAAATATGAAAACTTGACAACCGGTAATGGGTTTTTAAACTTCAAAACGGTGACGTTTGGTCGGAAGCTCCTCAACA
AGGTTTCCCAGCTTCAAATTACAAATAGCTATGGGAAAAAAGAAAGTTACCGGGCCTATATGGCAGAGTTGAGTTTATCT
GATGATGAAAGTGATAGTGACATCAAGTATGCGGTTGTCATGACCAATATCAGTCAACTAGAGCAGACCAGTGAAGAGCA
CGAAAGTCAAATCGCTCTCATCATGATCTGCTTCTGGGGAATCTCCTTATTCGCTAGCCTCTTCTTAGCACGTCTCAGCG
TCAAGCCCCTTCTTGAGAGTATGCAAAAGCAAAAGGCTTTCGTGGAAAATGCTTCCCATGAGTTGCGGACGCCTTTAGCA
GTTCTGCAAAATCGCCTCGAAACGCTTTTTAGAAAGCCTGAAGCGACCATTATGGAATCGAGTGAGAATATTGCATCCAG
CTTGGATGAAGTTCGAAATATGAAGCTTTTGACTACCAACCTTCTCAATATTGCCCGAAGAGATGACGGCTTGAAGCCAG
AGATGGAAGATATCGAACCAAGCTTTTTCGATCAGTCCTTCTCGAATTTTGAGATCATTGCAGAAGAAAATGGCAAAATC
TTCCGAGGAGACAATCAGGTGGACAAAGTCATTTGTTCTGATAGAACGCTCCTCAAGCAATTGATGACCATTCTCTATGA
CAATGCCTTGAAGTATACCGATGAAGATGGTGAGATCCAGTTTGAAGTTCAATTGAAGGATAAAAATCTTCTTTTGAGAG
TGCTGGATAATGGTTCAGGGATTCGAGATGAGGATAAGAAACGGATCTTTGATCGTTTTTACCGGGTCGACAAGGCCAGA
ACCCGTCAAAAAGGTGGATTTGGTTTGGGGTTATCCCTCGCTAAGCAGATCGTAGAAGCCTTTAAAGGGACCATTCAAGT
CAAAGATAATAAACCAAAAGGGACCATCTTTGAAGTGAAATTATCCATTAAGACGGAAAGTCGTAAAAAAAATCGTTCAT
AA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(334-442)

His Kinase A (phospho-acceptor) domain (HisKA)

(225-290)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60

99.338

0.596
  ciaH Streptococcus pneumoniae D39

60

99.338

0.596
  ciaH Streptococcus pneumoniae R6

60

99.338

0.596
  ciaH Streptococcus pneumoniae TIGR4

60

99.338

0.596
  ciaH Streptococcus mutans UA159

49.887

97.351

0.486