Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RIM74_RS02010 Genome accession   NZ_CP133955
Coordinates   381031..381717 (+) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. equi strain HTP133     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 376031..386717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM74_RS01990 (RIM74_01990) rsmG 377689..378402 (-) 714 WP_012680073.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  RIM74_RS01995 (RIM74_01995) - 378538..379095 (+) 558 WP_012677410.1 LemA family protein -
  RIM74_RS02000 (RIM74_02000) htpX 379132..380025 (+) 894 WP_012680072.1 zinc metalloprotease HtpX -
  RIM74_RS02005 (RIM74_02005) - 380313..380846 (+) 534 WP_050316018.1 DUF177 domain-containing protein -
  RIM74_RS02010 (RIM74_02010) covR 381031..381717 (+) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  RIM74_RS02015 (RIM74_02015) - 381721..383211 (+) 1491 WP_012680070.1 HAMP domain-containing histidine kinase -
  RIM74_RS02020 (RIM74_02020) nrdR 383402..383896 (+) 495 WP_012516251.1 transcriptional regulator NrdR -
  RIM74_RS02025 (RIM74_02025) - 383880..385043 (+) 1164 WP_173292518.1 helicase loader -
  RIM74_RS02030 (RIM74_02030) dnaI 385044..385952 (+) 909 WP_012680068.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=877850 RIM74_RS02010 WP_012516253.1 381031..381717(+) (covR) [Streptococcus equi subsp. equi strain HTP133]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=877850 RIM74_RS02010 WP_012516253.1 381031..381717(+) (covR) [Streptococcus equi subsp. equi strain HTP133]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCGCTTGAGCTACAGCATGAGGGTTA
CGAGGTGACCGTCGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGATTTGAAGTGACACGTCGATTGCAAACAGAAAAAACGACTTACATCATGATGATGACT
GCGCGTGACTCTATTATGGACGTTGTAGCTGGCTTGGATCGTGGTGCTGACGATTACATCGTGAAGCCATTTGCCATTGA
GGAATTGCTGGCGCGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAAGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTGTCTAACGTTTGGAAATATGA
CGAGGCTGTTGAAACTAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATCGATATCCCTGGGAAAGAGTCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425