Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RIM63_RS08785 Genome accession   NZ_CP133952
Coordinates   1798166..1798852 (-) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. zooepidemicus strain HT321     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1793166..1803852
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM63_RS08765 (RIM63_08765) dnaI 1793935..1794843 (-) 909 WP_012680068.1 primosomal protein DnaI -
  RIM63_RS08770 (RIM63_08770) - 1794844..1796007 (-) 1164 WP_317583881.1 helicase loader -
  RIM63_RS08775 (RIM63_08775) nrdR 1795991..1796485 (-) 495 WP_012516251.1 transcriptional regulator NrdR -
  RIM63_RS08780 (RIM63_08780) - 1796672..1798162 (-) 1491 WP_164336380.1 HAMP domain-containing histidine kinase -
  RIM63_RS08785 (RIM63_08785) covR 1798166..1798852 (-) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  RIM63_RS08790 (RIM63_08790) - 1799037..1799570 (-) 534 WP_317583884.1 DUF177 domain-containing protein -
  RIM63_RS08795 (RIM63_08795) htpX 1799859..1800752 (-) 894 WP_317583885.1 zinc metalloprotease HtpX -
  RIM63_RS08800 (RIM63_08800) - 1800784..1801341 (-) 558 WP_317583887.1 LemA family protein -
  RIM63_RS08805 (RIM63_08805) rsmG 1801478..1802191 (+) 714 WP_317583889.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=877781 RIM63_RS08785 WP_012516253.1 1798166..1798852(-) (covR) [Streptococcus equi subsp. zooepidemicus strain HT321]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=877781 RIM63_RS08785 WP_012516253.1 1798166..1798852(-) (covR) [Streptococcus equi subsp. zooepidemicus strain HT321]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCACTTGAGCTACAGCATGAGGGTTA
CGAGGTAACCGTTGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGGTTTGAAGTGACACGTCGCTTGCAAACAGAAAAAACGACTTACATCATGATGATGACA
GCGCGTGATTCTATTATGGACGTTGTAGCCGGCTTGGATCGTGGTGCTGATGATTACATCGTGAAGCCATTTGCCATTGA
AGAATTGCTGGCACGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAGGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTGTCTAACGTTTGGAAATATGA
CGAGGCTGTTGAGACCAATGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATAGATATCCCTGGGAAAGAGTCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425