Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   RIM63_RS07030 Genome accession   NZ_CP133952
Coordinates   1465115..1466467 (-) Length   450 a.a.
NCBI ID   WP_014623188.1    Uniprot ID   A0A6M1KZW6
Organism   Streptococcus equi subsp. zooepidemicus strain HT321     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1460115..1471467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM63_RS07015 (RIM63_07015) rnc 1460927..1461619 (-) 693 WP_038674782.1 ribonuclease III -
  RIM63_RS07020 (RIM63_07020) - 1461878..1463389 (-) 1512 WP_317583514.1 helix-turn-helix domain-containing protein -
  RIM63_RS07025 (RIM63_07025) vicX 1464302..1465111 (-) 810 WP_301899387.1 MBL fold metallo-hydrolase Regulator
  RIM63_RS07030 (RIM63_07030) vicK 1465115..1466467 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RIM63_RS07035 (RIM63_07035) vicR 1466460..1467170 (-) 711 WP_012677635.1 response regulator YycF Regulator
  RIM63_RS07040 (RIM63_07040) - 1467379..1468395 (-) 1017 WP_317583517.1 DUF3114 domain-containing protein -
  RIM63_RS07045 (RIM63_07045) - 1468441..1469703 (-) 1263 WP_317583519.1 AMP-binding protein -
  RIM63_RS07050 (RIM63_07050) - 1469693..1470808 (-) 1116 WP_317583520.1 acetyl-CoA C-acyltransferase -
  RIM63_RS07055 (RIM63_07055) - 1470805..1471344 (-) 540 WP_317583522.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51527.91 Da        Isoelectric Point: 5.5557

>NTDB_id=877771 RIM63_RS07030 WP_014623188.1 1465115..1466467(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain HT321]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=877771 RIM63_RS07030 WP_014623188.1 1465115..1466467(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain HT321]
ATGACTAAGGACATCATTGGAAACCTTTCTGCGTTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACGGACACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCCCCTTATACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACTTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTGGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAAGAGCGCGAGCGCAGACTCTTTGTTT
CAAATGTTAGCCATGAGCTGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATCGCTCCAAGCTTTATAAAGGTCTCACTGGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
CCTCTCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATCACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATCGAAAATATTTTAAACAATGCAATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGTATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGGAGTAGAGCTCAAGGAGGGACCGGC
TTAGGGCTGGCTATTGCTAAAGAAATTATTAAGCAGCACCGAGGCTTTATTTGGGCTAAGAGTGATTATGGCAAGGGCTC
AACCTTTACCATTGTGTTACCTTATGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M1KZW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631