Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   RHN62_RS10810 Genome accession   NZ_CP133937
Coordinates   2287395..2288729 (+) Length   444 a.a.
NCBI ID   WP_241951591.1    Uniprot ID   -
Organism   Pasteurella multocida strain AKS2021-HT3     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2282395..2293729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RHN62_RS10785 - 2282471..2285032 (-) 2562 WP_241951586.1 penicillin-binding protein 1A -
  RHN62_RS10790 - 2285168..2285941 (+) 774 WP_241951587.1 competence protein ComA -
  RHN62_RS10795 - 2285981..2286496 (+) 516 WP_241951588.1 competence protein ComB -
  RHN62_RS10800 - 2286496..2287020 (+) 525 WP_310549681.1 ATPase -
  RHN62_RS10805 - 2287023..2287385 (+) 363 WP_241951590.1 pilus assembly protein PilP -
  RHN62_RS10810 comE 2287395..2288729 (+) 1335 WP_241951591.1 type IV pilus secretin PilQ Machinery gene
  RHN62_RS10815 aroK 2288912..2289439 (+) 528 WP_005717623.1 shikimate kinase AroK -
  RHN62_RS10820 aroB 2289456..2290544 (+) 1089 WP_115173789.1 3-dehydroquinate synthase -
  RHN62_RS10825 - 2290548..2291453 (+) 906 WP_241951592.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  RHN62_RS10830 - 2291500..2291805 (-) 306 WP_241951593.1 DciA family protein -
  RHN62_RS10835 secM 2291898..2292209 (+) 312 WP_374762034.1 secA translation cis-regulator SecM -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 49285.64 Da        Isoelectric Point: 7.3925

>NTDB_id=877591 RHN62_RS10810 WP_241951591.1 2287395..2288729(+) (comE) [Pasteurella multocida strain AKS2021-HT3]
MWRAFRKISFVYFLCGVAYVGSSQAQDAEHFYLRLKQAPLVEMLQYLALQQHQDLLIDDHLEGTLSLQMKKTTFEKCLQS
IARMKQLELHQEGKSYYLTSPSGVAANDTHHPTSLMTSSIKLHFAKAAEVVKSLTSGQGSLLSVGGSLSFDERTNLLLIQ
DEPQSIQRIKALVAEMDKPIEQIAIEARIVTMTDESLQELGVRWGLFQATEQAHTIAGSLAANGFSNIENQLNVNFSTNS
APVGSIALQLAKINGRLLDLELTALEREKHIEIIASPRLLTTNKKSASIKQGTEIPYVMKRGKDKSESVEFREAVLGLDV
TPHISKDNTILLDLLITQNTLGAPVVYDKGEIVSIDKQEINTQVVAQDGETIVLGGVFHDTMTKGVNKVPLLGDLPLLKH
VFSQETERHQKRELVIFVTPHIIKPTQSSPEQKTTRVKKSAKSR

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=877591 RHN62_RS10810 WP_241951591.1 2287395..2288729(+) (comE) [Pasteurella multocida strain AKS2021-HT3]
ATGTGGCGAGCATTCAGAAAAATATCTTTTGTGTACTTTTTATGTGGAGTTGCTTATGTTGGAAGTAGTCAAGCACAAGA
CGCAGAACATTTTTATTTACGTTTAAAACAAGCGCCTTTAGTCGAAATGTTACAGTATTTAGCATTACAACAACATCAGG
ATTTGTTAATCGATGATCATTTAGAGGGCACATTATCATTACAGATGAAAAAGACAACCTTTGAGAAATGTTTACAGTCG
ATTGCAAGAATGAAACAACTTGAGTTACATCAAGAAGGGAAATCCTATTATTTAACTTCCCCTTCAGGTGTTGCAGCAAA
CGATACTCATCATCCTACGTCATTGATGACATCTTCAATAAAATTGCATTTTGCCAAAGCTGCAGAGGTAGTGAAATCTT
TAACTTCAGGGCAGGGAAGTTTACTTTCTGTCGGGGGGAGTTTGAGTTTTGATGAGCGGACTAATTTACTGCTGATTCAG
GATGAACCGCAATCGATACAGCGTATTAAAGCATTAGTAGCAGAAATGGATAAACCCATTGAACAAATTGCGATCGAAGC
CAGAATTGTGACGATGACAGACGAAAGTTTGCAGGAACTTGGCGTAAGATGGGGGCTATTTCAAGCAACAGAACAGGCAC
ATACTATTGCTGGGAGTTTAGCTGCAAACGGCTTTTCAAATATAGAAAACCAATTAAATGTGAATTTCTCGACCAATAGT
GCACCAGTTGGTTCCATCGCCCTACAGTTGGCGAAAATAAATGGTCGATTATTAGACTTGGAATTAACTGCCTTGGAACG
AGAAAAGCATATTGAGATTATTGCGAGTCCTCGTTTATTAACAACGAATAAAAAAAGTGCCAGTATTAAACAAGGGACGG
AAATTCCTTATGTGATGAAACGGGGAAAAGATAAAAGCGAATCGGTGGAATTTCGAGAAGCTGTATTAGGTTTAGATGTG
ACACCGCATATCTCAAAAGACAACACGATTTTATTAGATTTATTGATTACACAAAATACATTAGGTGCACCGGTAGTGTA
TGATAAAGGCGAAATTGTTTCGATCGATAAACAGGAAATCAATACTCAAGTCGTCGCGCAAGATGGTGAAACCATCGTTT
TAGGCGGGGTGTTTCATGATACGATGACAAAGGGAGTCAATAAAGTACCACTACTAGGGGATTTGCCTTTGCTTAAACAT
GTGTTTAGCCAGGAAACTGAACGTCATCAAAAGCGGGAATTAGTGATTTTTGTCACGCCTCATATTATCAAACCGACCCA
AAGTTCGCCTGAACAAAAAACAACGAGAGTTAAAAAATCTGCAAAATCAAGGTGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(264-424)

Bacterial type II/III secretion system short domain (Secretin_N)

(119-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

62.125

97.523

0.606
  comE Haemophilus influenzae 86-028NP

61.432

97.523

0.599
  comE Glaesserella parasuis strain SC1401

48.611

97.297

0.473
  pilQ Vibrio campbellii strain DS40M4

39.524

94.595

0.374
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

39.806

92.793

0.369
  pilQ Vibrio cholerae strain A1552

39.806

92.793

0.369