Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   RDV58_RS02090 Genome accession   NZ_CP133475
Coordinates   417302..417595 (+) Length   97 a.a.
NCBI ID   WP_002263439.1    Uniprot ID   -
Organism   Streptococcus mutans strain LMG 14558     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 412302..422595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV58_RS02065 (RDV58_02065) - 414204..414587 (+) 384 WP_002264248.1 DUF1033 family protein -
  RDV58_RS02070 (RDV58_02070) comYA 414717..415658 (+) 942 WP_002264247.1 competence type IV pilus ATPase ComGA Machinery gene
  RDV58_RS02075 (RDV58_02075) comYB 415594..416625 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  RDV58_RS02080 (RDV58_02080) comYC 416625..416939 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  RDV58_RS02085 (RDV58_02085) comYD 416926..417330 (+) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  RDV58_RS02090 (RDV58_02090) comYE 417302..417595 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  RDV58_RS02095 (RDV58_02095) comYF 417582..418016 (+) 435 WP_002264245.1 competence type IV pilus minor pilin ComGF Machinery gene
  RDV58_RS02100 (RDV58_02100) comYG 417994..418383 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  RDV58_RS02105 (RDV58_02105) comYH 418438..419391 (+) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  RDV58_RS02110 (RDV58_02110) - 419450..420649 (+) 1200 WP_002263443.1 acetate kinase -
  RDV58_RS02115 (RDV58_02115) - 421202..421447 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  RDV58_RS02120 (RDV58_02120) - 421416..421856 (+) 441 WP_002263445.1 hypothetical protein -
  RDV58_RS02125 (RDV58_02125) - 421909..422571 (+) 663 WP_002266816.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11001.91 Da        Isoelectric Point: 9.4908

>NTDB_id=874572 RDV58_RS02090 WP_002263439.1 417302..417595(+) (comYE) [Streptococcus mutans strain LMG 14558]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALQTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=874572 RDV58_RS02090 WP_002263439.1 417302..417595(+) (comYE) [Streptococcus mutans strain LMG 14558]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGACTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

100

100

1
  comYE Streptococcus mutans UA159

100

100

1
  comGE/cglE Streptococcus pneumoniae Rx1

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae D39

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae R6

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae TIGR4

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis NCTC 12261

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis SK321

44.444

92.784

0.412