Detailed information NTG0874457

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: RDV54_RS00315
• Genome accession: NZ_CP133471
• Coordinates: 48576..49235 (-)
• Length: 219 a.a.
• NCBI ID: WP_000608383.1
• Uniprot ID: A0AAX2L6K8
• Organism: Streptococcus mitis strain LMG 14557
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 43576..54235

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV54_RS00285 (RDV54_00285)	-	43697..44263 (+)	567	WP_000601911.1	aminodeoxychorismate/anthranilate synthase component II	-
RDV54_RS00290 (RDV54_00290)	trpD	44274..45278 (+)	1005	WP_000658712.1	anthranilate phosphoribosyltransferase	-
RDV54_RS00295 (RDV54_00295)	trpC	45275..46048 (+)	774	WP_000076529.1	indole-3-glycerol phosphate synthase TrpC	-
RDV54_RS00300 (RDV54_00300)	-	46035..46634 (+)	600	WP_000169924.1	phosphoribosylanthranilate isomerase	-
RDV54_RS00305 (RDV54_00305)	trpB	46612..47835 (+)	1224	WP_000331264.1	tryptophan synthase subunit beta	-
RDV54_RS00310 (RDV54_00310)	trpA	47828..48604 (+)	777	WP_001127014.1	tryptophan synthase subunit alpha	-
RDV54_RS00315 (RDV54_00315)	cclA/cilC	48576..49235 (-)	660	WP_000608383.1	prepilin peptidase	Machinery gene
RDV54_RS00320 (RDV54_00320)	-	49305..49760 (+)	456	WP_000155436.1	GNAT family N-acetyltransferase	-
RDV54_RS09020	-	49796..50070 (+)	275	Protein_42	transposase	-
RDV54_RS00325 (RDV54_00325)	-	50180..50383 (-)	204	WP_000109960.1	CsbD family protein	-
RDV54_RS00330 (RDV54_00330)	-	50414..51022 (-)	609	WP_000064112.1	Asp23/Gls24 family envelope stress response protein	-
RDV54_RS00335 (RDV54_00335)	-	51060..51230 (-)	171	WP_000455069.1	DUF2273 domain-containing protein	-
RDV54_RS00340 (RDV54_00340)	amaP	51242..51814 (-)	573	WP_000047598.1	alkaline shock response membrane anchor protein AmaP	-
RDV54_RS00345 (RDV54_00345)	-	51891..52126 (-)	236	Protein_47	GlsB/YeaQ/YmgE family stress response membrane protein	-
RDV54_RS00350 (RDV54_00350)	-	52503..53368 (+)	866	Protein_48	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24965.33 Da
• Isoelectric Point: 8.1626

>NTDB_id=874457 RDV54_RS00315 WP_000608383.1 48576..49235(-) (cclA/cilC) [Streptococcus mitis strain LMG 14557]
MINIYFFLVGSILASFLGLVIDRFPEQSIIQPASHCDSCHTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYAFFELGLG
LLFLAWSLGWLSLGQVILITAGLTLGIYDFRHQEYPLLVWMTFHIILMAFCGWSLIMLFFLVLGIIAHFIDIRMGAGDFL
FLASCSIVFSVTELLILIQFASAMGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=874457 RDV54_RS00315 WP_000608383.1 48576..49235(-) (cclA/cilC) [Streptococcus mitis strain LMG 14557]
ATGATTAATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTTATTGACCGTTTCCCAGAGCA
ATCCATTATCCAACCTGCTAGTCACTGCGATTCCTGTCATACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCGC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTTCGCTATCCTGTCTGGTATGCCTTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTAGCTTGGTCTTTGGGCTGGCTTTCCTTGGGTCAAGTCATCCTGATAACTGCCGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTAGTCTGGATGACTTTTCATATAATCCTCATGGCTTTCTGTGGTTGGA
GTCTGATTATGCTCTTCTTTCTTGTTCTAGGAATAATAGCCCATTTTATCGATATCCGTATGGGAGCAGGGGATTTTCTC
TTTTTAGCTTCTTGTTCTATCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAATTTGCTTCTGCGATGGGAATTCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTACCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-86)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis NCTC 12261	100	100	1
cclA/cilC	Streptococcus mitis SK321	88.128	100	0.881
cclA/cilC	Streptococcus pneumoniae Rx1	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae D39	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae R6	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae TIGR4	87.215	100	0.872