Detailed information NTG0874371

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: WJ054_RS10445
• Genome accession: NZ_CP149485
• Coordinates: 2128695..2131250 (-)
• Length: 851 a.a.
• NCBI ID: WP_012767643.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain STG643
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2123695..2136250

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WJ054_RS10420 (WJ054_10405)	-	2123821..2124174 (-)	354	WP_003058738.1	glyoxalase/bleomycin resistance/extradiol dioxygenase family protein	-
WJ054_RS10425 (WJ054_10410)	-	2124177..2124749 (-)	573	WP_003058799.1	DNA-3-methyladenine glycosylase I	-
WJ054_RS10430 (WJ054_10415)	ruvA	2124759..2125352 (-)	594	WP_003058778.1	Holliday junction branch migration protein RuvA	Machinery gene
WJ054_RS10435 (WJ054_10420)	-	2125354..2126574 (-)	1221	WP_111679470.1	MFS transporter	-
WJ054_RS10440 (WJ054_10425)	hexB	2126585..2128567 (-)	1983	WP_012767642.1	DNA mismatch repair endonuclease MutL	Machinery gene
WJ054_RS10445 (WJ054_10430)	hexA	2128695..2131250 (-)	2556	WP_012767643.1	DNA mismatch repair protein MutS	Machinery gene
WJ054_RS10450 (WJ054_10435)	-	2131237..2131590 (-)	354	WP_012767644.1	YlbF family regulator	-
WJ054_RS10455 (WJ054_10440)	argR	2131587..2132024 (-)	438	WP_003055516.1	arginine repressor	-
WJ054_RS10460 (WJ054_10445)	argS	2132313..2134004 (+)	1692	WP_015017500.1	arginine--tRNA ligase	-
WJ054_RS10465 (WJ054_10450)	-	2134074..2135471 (-)	1398	WP_014612639.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95288.71 Da
• Isoelectric Point: 4.8790

>NTDB_id=874371 WJ054_RS10445 WP_012767643.1 2128695..2131250(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain STG643]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSAYVDKLVNDIDSLPELEYLIRTAIDP
DAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAAVAETNHYIRPQFN
DNHVIKIQEGRHAVVEKVMGVQEYIPNSISFNQETSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTMFATHYHEL
TDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADEVLTRLEAQAQSAEIISVPSKV
EPSSAAREGQLSLFPDEDKSQEIIHTLEAIDVMNMTPLQAMTTLYELKKLL

Nucleotide

• Length: 2556 bp

>NTDB_id=874371 WJ054_RS10445 WP_012767643.1 2128695..2131250(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain STG643]
ATGGCAAAAGCTAACATTTCTCCTGGGATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTATGAATTATTTTATGATGATGCTGTCAAAGCAGCACAACTCTTAGAAATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCCATGGCAGGCGTGCCACATCATTCTGCCCAACAATACATTGATGTGTTAATT
GAGTTGGGTTACAAGGTTGCTGTCGCAGAACAAATGGAAGACCCAAAGCAAGCTGTTGGGGTGGTGAAGCGTGAGGTCGT
TCAAGTCATCACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTGCCGTTATGGATTGGCTTATATGGATGTGTCCACAGGTGAATTTTGCGTGACAGATTTGGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGACGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAAGAAACGGTCTATGAAGATAAATCTTTAATTGACGGTCAATTGACAA
CGGTAGAACTGACAGCGGCAGGAAAACTCTTGCAATACGTTCACAAAACACAAATGCGAGAACTCAGCCACTTGCAAGCC
TTGGTTCACTATGAAATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTCTAGATTTGGTAGAGAATGCTAG
AACGAATAAAAAACATGGGAGTCTGTATTGGCTGTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCTATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACAGATTTAAGCAATAGCTTAAAAGGTGTTTACGATATCGAACGCTTATCTAGCCGTGTGTCTTTTGGCAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCCCAAGTGCCTTATATCAAAGCCATATTAGAGTCTTTTAACA
GCGCTTATGTTGACAAACTTGTCAATGATATTGACAGTTTGCCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAAGGAAGTATTATCCGCAATGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTAAT
GCGAGAGGGGACAGGCTGGATTGCGGATATTGAGGCCAAAGAGCGTCAAGCAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTTCATGTTACGAATTCAAATCTTAGCTTAGTTCCCGACCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCTGAGCGTTATGGAACAGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAGTC
ATCTAGTTTAGAATACGATATTTTTATGTGTATTCGAGCTCAAGTTGAAACCTATATTAATCGTTTACAGAAACTGGCTA
AAACTTTGGCAACGGTGGATGTTTTGCAAAGTTTAGCAGCCGTTGCCGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTAAAATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGCAGGAATACATTCCCAA
TAGTATCTCTTTTAACCAAGAGACAAGCATTCAATTGATTACAGGTCCAAATATGAGCGGTAAGTCGACTTATATGAGAC
AGCTGGCCTTAACGGTTATTATGGCCCAGATGGGCTCATTTGTAGCTGCTGACCATGTTGATTTGCCTCTATTTGATGCG
ATTTTTACGCGTATTGGGGCTGCTGATGATTTGATTTCTGGGCAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCAATCAAACGAGCCAGTGACAATTCCCTTATTCTATTTGATGAACTAGGGAGGGGTACGGCAACTTATGATGGTATGG
CACTGGCTCAGGCAATTATCGAATATATCCATGATAGAGTTGGTGCTAAGACCATGTTTGCAACGCACTATCATGAGTTG
ACAGACTTGTCAACTAAGTTGACAAGTCTAGTCAATGTTCATGTAGCAACGCTTGAAAAAGATGGCGATGTAACCTTCCT
TCATAAGATTGCTGAGGGACCGGCGGATAAATCTTACGGTATTCATGTAGCAAAAATAGCAGGACTTCCTGAGGCCCTGC
TAAGCAGAGCAGATGAGGTGCTTACGCGTTTAGAAGCGCAAGCACAATCTGCTGAGATAATATCAGTCCCTTCAAAAGTT
GAGCCAAGCAGCGCTGCTAGAGAGGGACAGTTATCGCTGTTTCCTGATGAGGATAAGTCTCAGGAGATTATTCACACGTT
AGAAGCTATTGATGTGATGAACATGACTCCACTTCAAGCAATGACAACCCTTTACGAATTGAAAAAGTTGTTATAG

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	70.975	100	0.71
mutS	Pseudomonas stutzeri strain ATCC 17587	36.842	100	0.37