Detailed information NTG0874239

Bioinformatically predicted

Overview

• Name: comP
• Type: Regulator
• Locus tag: RDU00_RS15990
• Genome accession: NZ_CP133449
• Coordinates: 3009055..3011364 (-)
• Length: 769 a.a.
• NCBI ID: WP_003242894.1
• Uniprot ID: Q99027
• Organism: Bacillus subtilis strain KK195
• Function: phosphorylation of ComA (predicted from homology) Competence regulation

Genomic Context

Location: 3004055..3016364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDU00_RS15950 (RDU00_15940)	mrpB	3004522..3004953 (+)	432	WP_003228819.1	Na(+)/H(+) antiporter subunit B	-
RDU00_RS15955 (RDU00_15945)	mrpC	3004953..3005294 (+)	342	WP_003220730.1	Na(+)/H(+) antiporter subunit C	-
RDU00_RS15960 (RDU00_15950)	mrpD	3005287..3006768 (+)	1482	WP_003244432.1	Na+/H+ antiporter subunit D	-
RDU00_RS15965 (RDU00_15955)	mrpE	3006774..3007250 (+)	477	WP_003244015.1	Na+/H+ antiporter subunit E	-
RDU00_RS15970 (RDU00_15960)	mrpF	3007250..3007534 (+)	285	WP_003228814.1	Na(+)/H(+) antiporter subunit F1	-
RDU00_RS15975 (RDU00_15965)	mnhG	3007518..3007892 (+)	375	WP_003244302.1	monovalent cation/H(+) antiporter subunit G	-
RDU00_RS15980 (RDU00_15970)	yuxO	3007931..3008311 (-)	381	WP_003228810.1	hotdog fold thioesterase	-
RDU00_RS15985 (RDU00_15975)	comA	3008330..3008974 (-)	645	WP_003220716.1	two-component system response regulator ComA	Regulator
RDU00_RS15990 (RDU00_15980)	comP	3009055..3011364 (-)	2310	WP_003242894.1	two-component system sensor histidine kinase ComP	Regulator
RDU00_RS15995 (RDU00_15985)	comX	3011379..3011546 (-)	168	WP_003242801.1	competence pheromone ComX	Regulator
RDU00_RS16000 (RDU00_15990)	comQ	3011534..3012433 (-)	900	WP_003243039.1	ComX modifying isoprenyl transferase ComQ	Regulator
RDU00_RS16005 (RDU00_15995)	degQ	3012618..3012758 (-)	141	WP_003220708.1	degradation enzyme regulation protein DegQ	Regulator
RDU00_RS16010 (RDU00_16000)	-	3012980..3013105 (+)	126	WP_003228793.1	hypothetical protein	-
RDU00_RS16015 (RDU00_16005)	-	3013219..3013587 (+)	369	WP_003243784.1	hypothetical protein	-
RDU00_RS16020 (RDU00_16010)	pdeH	3013563..3014792 (-)	1230	WP_003243525.1	cyclic di-GMP phosphodiesterase	-

Sequence

Protein

• Length: 769 a.a.
• Molecular weight: 89308.77 Da
• Isoelectric Point: 8.2618

>NTDB_id=874239 RDU00_RS15990 WP_003242894.1 3009055..3011364(-) (comP) [Bacillus subtilis strain KK195]
MKNLIKKFTIAVIVLSILYISYTTYISMNGIIIGTKIHKNDKSQFMIEEISESSYGQFVGLRQGDIILKINKEKPSDKHL
KWGYLSHINSLDILRSGKKIHLKDFDLVTLNRPYSFFLFVLPLFFYFLSIICIFYILKVNKKRRSFAAYILILLLLDISI
AYISAGGPFRGHIINRYINLFTFISSPILYLQFIQRYLGEIGKTFLNRISFLYIIPIFNLGIEFFQDYLQVDIDFLATLN
LVSFATLTLFSFSAIYLHLNKYKYAEHSFILKLLILTNTLSFAPFLIFFVLPIIFTGNYIFPALASASLLVLIPFGLVYQ
FVANKMFDIEFILGRMRYYALLAMIPTLLIVGALVLFDVMDIQMNPVRQTVFFFVVMFAVFYFKEVMDFKFRLKRFSEKF
NYQDSIFKYTQLMRGVTSLQQVFKELKNTILDVLLVSKAYTFEVTPDHKVIFLDKHEVGPDWNFYQEEFENVTSEIGKII
EVNQGFLMKVGERGGSSYVLLCLSNINTPRLTRDEISWLKTLSFYTSVSMENVLHIEELMEHLKDLKQEGTNPIWLKKLM
FAIEEKQRSGLARDLHDSVLQDLISLKRQCELFLGDFKKDDNPCREEVQDKLVQMNEQMSDVISMTRETCHELRPQLLYD
LGLVKALSKLVAQQQERVPFHIRLNTGRFTASLDLDSQLNLYRIIQEFLSNAVKHSQATDVLIMLISIQNKIVLHYEDDG
VGFDQEKNTEHSMSMGLSGIKERVRALDGRLRIETSEGKGFKADIEIEL

Nucleotide

• Length: 2310 bp

>NTDB_id=874239 RDU00_RS15990 WP_003242894.1 3009055..3011364(-) (comP) [Bacillus subtilis strain KK195]
TTGAAGAACTTAATAAAAAAATTCACAATAGCTGTAATTGTTTTGAGTATCCTTTATATAAGCTATACAACTTATATCAG
TATGAATGGAATTATTATTGGGACTAAGATTCATAAAAATGATAAAAGTCAATTTATGATAGAAGAAATATCGGAATCTT
CATATGGACAATTTGTTGGTCTGAGACAGGGAGACATCATATTAAAAATTAATAAAGAAAAACCTTCAGACAAACATTTG
AAATGGGGATATTTGAGTCATATTAACAGTCTGGATATTTTGAGAAGTGGAAAAAAGATTCATCTCAAAGATTTTGATTT
AGTTACTCTAAATAGACCTTATAGTTTTTTTCTGTTCGTACTTCCTTTGTTTTTTTATTTTTTAAGCATAATATGTATTT
TTTATATACTTAAAGTAAATAAAAAAAGGAGATCATTTGCTGCCTATATTCTTATTCTATTGTTATTAGACATTTCGATA
GCATATATAAGTGCAGGCGGACCATTTAGAGGACATATAATCAATCGGTATATTAACTTGTTTACTTTTATATCTTCTCC
TATTCTTTATCTTCAATTTATACAAAGATACCTTGGAGAAATAGGTAAAACTTTTTTGAATAGAATTTCTTTTCTTTATA
TCATACCAATATTTAATCTTGGTATTGAGTTTTTTCAAGACTATTTACAAGTAGATATTGATTTTTTAGCAACTCTTAAT
TTGGTTTCTTTTGCAACTTTGACTCTATTTTCTTTTTCAGCGATATACTTACATCTTAATAAATATAAATATGCTGAGCA
TTCGTTTATTCTTAAATTACTAATTTTAACAAACACTCTTTCATTTGCGCCTTTTTTGATATTTTTTGTTCTTCCAATAA
TATTTACAGGTAATTATATTTTCCCGGCATTAGCTTCGGCGTCATTACTAGTACTAATTCCGTTCGGGTTAGTATACCAA
TTTGTAGCCAATAAGATGTTTGATATAGAGTTTATCTTAGGAAGAATGAGATACTATGCTCTACTTGCCATGATACCAAC
TCTTCTAATAGTTGGTGCATTAGTTCTGTTTGATGTAATGGACATCCAGATGAACCCTGTGCGTCAAACTGTATTTTTTT
TCGTTGTCATGTTCGCTGTCTTTTATTTTAAAGAGGTCATGGATTTTAAATTTCGGTTAAAACGTTTCTCCGAAAAATTC
AACTATCAGGACAGTATTTTTAAATATACTCAGCTAATGAGGGGTGTAACTTCTCTTCAACAAGTTTTTAAAGAACTGAA
AAATACTATACTGGATGTTTTGCTTGTAAGCAAAGCTTATACCTTTGAGGTTACTCCTGATCACAAAGTGATATTTTTAG
ATAAGCATGAAGTTGGACCGGACTGGAATTTTTATCAAGAGGAATTTGAAAACGTAACTTCAGAAATTGGGAAAATTATA
GAAGTCAATCAAGGCTTTCTTATGAAAGTTGGTGAACGAGGCGGTAGTTCTTATGTTCTGCTTTGTTTATCTAATATTAA
CACTCCCCGGCTAACACGTGATGAAATATCGTGGCTGAAAACACTGTCTTTTTATACAAGTGTGTCCATGGAAAATGTCC
TGCATATTGAGGAGCTCATGGAACATTTGAAGGACTTAAAACAAGAGGGAACCAACCCCATCTGGCTGAAAAAGCTAATG
TTTGCAATCGAAGAAAAACAGCGTTCAGGACTCGCCCGCGATCTCCACGATTCGGTTCTTCAGGATTTGATTTCCTTAAA
ACGCCAGTGTGAGCTGTTTTTGGGTGATTTCAAGAAGGATGATAATCCGTGCCGTGAAGAGGTGCAGGACAAGCTTGTAC
AGATGAATGAGCAGATGTCTGATGTGATTTCGATGACGAGGGAGACGTGTCATGAGCTGCGGCCGCAGCTTCTGTATGAT
CTTGGATTGGTGAAGGCGCTGTCGAAGCTGGTGGCGCAGCAGCAGGAGCGGGTTCCGTTTCATATCCGTTTAAATACCGG
GAGATTTACGGCTTCCCTTGATCTGGATTCGCAGCTGAATTTGTACCGGATCATTCAAGAGTTTCTGTCTAATGCGGTCA
AGCACTCTCAGGCGACGGATGTGCTGATTATGCTCATCAGTATTCAAAACAAAATCGTTCTTCATTATGAGGACGATGGC
GTTGGGTTTGATCAAGAAAAAAATACTGAGCATTCCATGAGCATGGGGCTTTCTGGCATTAAGGAGAGAGTCAGGGCTTT
AGATGGGCGCCTTCGGATTGAAACAAGTGAAGGAAAGGGCTTTAAGGCTGATATTGAAATCGAATTGTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (568-638)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (679-765)

3D structure

• AlphaFold DB: Q99027

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Bacillus subtilis subsp. subtilis str. 168	100	100	1