Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SHJJP9002_RS04565 Genome accession   NZ_CP133006
Coordinates   984770..985399 (+) Length   209 a.a.
NCBI ID   WP_046837881.1    Uniprot ID   A0A1S2MGW6
Organism   Staphylococcus casei strain SCK7     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 979770..990399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SHJJP9002_RS04535 (SHJJP9002_000905) - 979806..980525 (+) 720 WP_069824827.1 glutamine amidotransferase -
  SHJJP9002_RS04540 (SHJJP9002_000906) - 980618..981604 (-) 987 WP_046837886.1 aromatic acid exporter family protein -
  SHJJP9002_RS04545 (SHJJP9002_000907) map 981779..982531 (+) 753 WP_069824826.1 type I methionyl aminopeptidase -
  SHJJP9002_RS04550 (SHJJP9002_000908) - 982636..983022 (+) 387 WP_069824825.1 hypothetical protein -
  SHJJP9002_RS04555 (SHJJP9002_000909) liaF 983039..983740 (+) 702 WP_069824824.1 cell wall-active antibiotics response protein LiaF -
  SHJJP9002_RS04560 (SHJJP9002_000910) vraS 983737..984780 (+) 1044 WP_046837882.1 sensor histidine kinase Regulator
  SHJJP9002_RS04565 (SHJJP9002_000911) vraR 984770..985399 (+) 630 WP_046837881.1 response regulator transcription factor Regulator
  SHJJP9002_RS04570 (SHJJP9002_000912) - 985596..986741 (-) 1146 WP_069824823.1 YihY/virulence factor BrkB family protein -
  SHJJP9002_RS04575 (SHJJP9002_000913) - 986957..987241 (-) 285 WP_046837879.1 hypothetical protein -
  SHJJP9002_RS04580 (SHJJP9002_000914) - 987241..987711 (-) 471 WP_069824822.1 low molecular weight protein-tyrosine-phosphatase -
  SHJJP9002_RS04585 (SHJJP9002_000915) - 987845..988051 (+) 207 WP_256121787.1 DUF1128 family protein -
  SHJJP9002_RS04590 (SHJJP9002_000916) - 988067..989308 (+) 1242 WP_341636897.1 aminopeptidase -
  SHJJP9002_RS04595 (SHJJP9002_000917) - 989483..990004 (+) 522 WP_069824820.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23702.20 Da        Isoelectric Point: 4.6181

>NTDB_id=871293 SHJJP9002_RS04565 WP_046837881.1 984770..985399(+) (vraR) [Staphylococcus casei strain SCK7]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGNEAIEKAHQLNPDLILMDLLMDDMDGVEATELIKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=871293 SHJJP9002_RS04565 WP_046837881.1 984770..985399(+) (vraR) [Staphylococcus casei strain SCK7]
ATGCCGATTAAAGTTTTATTTGTTGATGATCACGAAATGGTACGAATAGGTATTTCTAGTTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGTAAGTCAGGGAATGAAGCGATAGAAAAAGCACATCAACTTAATCCAGATTTAATCCTCA
TGGACTTACTTATGGATGATATGGATGGTGTAGAAGCTACAGAACTTATCAAAAAAGATTTACCTCATATTAAAGTGGTC
ATGTTAACAAGTTACATTGAGGATAATGAAGTATACCGCGCCTTAGATTCAGGTGTGGACAGTTATATTTTAAAAACTAC
AAGCGCAAGTGATATTGCTGAAGCAATACGTAAGACATATAATGATGAGTCTGTATTTGAAGCAGAAGTATTAGTGAAAA
TGAGAAATAGAATGAAACAACGTGCTGAGTTATATGAAATGCTTACAGAACGTGAGATGGAAATTTTATTACTTATTGCT
AAAGGATACTCGAATCAAGAAATAGCTAGTGCTTCACATATTACAATCAAAACCGTCAAGACCCATGTAAGTAATATATT
AAGTAAATTAGAAGTACAAGATAGAACACAAGCAGTTATTTATGCGTTCCAACATAATTTAATACAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S2MGW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364