NTDB

Overview

Name	vicR	Type	Regulator
Locus tag	Q9317_RS06920	Genome accession	NZ_CP132230
Coordinates	1407521..1408246 (-)	Length	241 a.a.
NCBI ID	WP_003101290.1	Uniprot ID	A0A3L8GIX6
Organism	Streptococcus iniae strain BH15-2
Function	repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1402521..1413246

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q9317_RS06895 (Q9317_06895)	-	1402832..1403443 (-)	612	WP_016356076.1	phosphate ABC transporter ATP-binding protein	-
Q9317_RS06900 (Q9317_06900)	pstA	1403446..1404261 (-)	816	WP_121791527.1	phosphate ABC transporter permease PstA	-
Q9317_RS06905 (Q9317_06905)	pstC	1404254..1405117 (-)	864	WP_003101285.1	phosphate ABC transporter permease subunit PstC	-
Q9317_RS06910 (Q9317_06910)	-	1405180..1406055 (-)	876	WP_305981536.1	substrate-binding domain-containing protein	-
Q9317_RS06915 (Q9317_06915)	pnpS	1406209..1407537 (-)	1329	WP_003101288.1	two-component system histidine kinase PnpS	-
Q9317_RS06920 (Q9317_06920)	vicR	1407521..1408246 (-)	726	WP_003101290.1	response regulator transcription factor	Regulator
Q9317_RS06925 (Q9317_06925)	-	1408342..1408725 (-)	384	WP_003101292.1	VOC family protein	-
Q9317_RS06930 (Q9317_06930)	-	1408918..1409061 (+)	144	WP_003101294.1	SPJ_0845 family protein	-
Q9317_RS06935 (Q9317_06935)	-	1409061..1409966 (+)	906	WP_003101296.1	permease	-
Q9317_RS06940 (Q9317_06940)	-	1409963..1410778 (+)	816	WP_003101297.1	TIGR03943 family protein	-
Q9317_RS06945 (Q9317_06945)	-	1410850..1411476 (-)	627	WP_003101299.1	NAD(P)-dependent oxidoreductase	-
Q9317_RS06950 (Q9317_06950)	-	1411763..1413139 (-)	1377	WP_003101303.1	PTS sugar transporter subunit IIC	-

Sequence

Protein

Download Length: 241 a.a. Molecular weight: 28088.34 Da Isoelectric Point: 5.1365

                                >NTDB_id=867892 Q9317_RS06920 WP_003101290.1 1407521..1408246(-) (vicR) [Streptococcus iniae strain BH15-2]

MKKTVLLVDDEEHILRLLDYHLSKEGFSIDTATDGRSALKLAETESYDFILLDIMLPQLDGIEVCKRIRAKNSKTPIMMV

SAKGEEFDKVLALELGADDYMTKPFSPRELLARVKAILRRTGKDDSQQEEFGFADQRFLVNDLVIYPERNEVYKEQDLIS

LTPKEYELLMYLVKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDDPKNPEMIKTIRGYGYQFKEMKDATK

S

Nucleotide

Download Length: 726 bp

                                >NTDB_id=867892 Q9317_RS06920 WP_003101290.1 1407521..1408246(-) (vicR) [Streptococcus iniae strain BH15-2]

ATGAAAAAGACAGTTTTATTAGTAGACGACGAAGAGCACATCTTACGTTTATTAGACTATCATCTCAGCAAGGAAGGCTT

TAGTATTGACACAGCAACAGATGGCAGATCAGCACTAAAATTAGCTGAAACAGAAAGTTATGACTTCATTTTGTTAGACA

TCATGTTGCCCCAATTGGACGGTATTGAGGTCTGTAAACGTATCAGAGCTAAAAATAGTAAGACCCCTATTATGATGGTA

TCAGCTAAAGGGGAAGAATTTGACAAGGTCCTAGCCTTAGAACTAGGAGCTGATGATTACATGACAAAACCCTTTAGTCC

AAGGGAATTGCTGGCGCGTGTAAAAGCTATTTTAAGACGAACAGGAAAAGACGACAGCCAACAAGAAGAGTTTGGCTTCG

CTGACCAGCGATTCTTGGTCAATGACTTGGTCATTTACCCTGAAAGAAATGAAGTTTACAAAGAGCAAGACTTGATTTCC

TTAACCCCAAAAGAGTATGAACTGTTAATGTATTTAGTCAAACATCCCAATATGACCTTAACAAGAGAACGACTTTTAGA

ACGGATTTGGGGGTATGACTTTGGCCAAGAAACACGTTTAGTAGATGTTCATATTGGAAAATTAAGAGACAAAATTGAAG

ATGATCCTAAAAATCCAGAGATGATTAAAACAATCAGGGGCTATGGCTATCAGTTTAAGGAGATGAAGGATGCTACAAAA

TCTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A3L8GIX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
vicR	Streptococcus mutans UA159	51.293	96.266	0.494
micA	Streptococcus pneumoniae Cp1015	48.918	95.851	0.469
covR	Lactococcus lactis subsp. lactis strain DGCC12653	42.194	98.34	0.415
covR	Streptococcus salivarius strain HSISS4	39.316	97.095	0.382

Detailed information NTG0867892