Detailed information NTG0867073

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: Q8W18_RS16740
• Genome accession: NZ_CP132058
• Coordinates: 3231964..3233139 (-)
• Length: 391 a.a.
• NCBI ID: WP_024719243.1
• Uniprot ID: A0A081LEM4
• Organism: Bacillus pumilus strain F12-21
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3226964..3238139

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q8W18_RS16710 (Q8W18_16710)	-	3227132..3227551 (-)	420	WP_034660147.1	TIGR03826 family flagellar region protein	-
Q8W18_RS16715 (Q8W18_16715)	comFC	3227608..3228294 (-)	687	WP_306011282.1	ComF family protein	Machinery gene
Q8W18_RS16720 (Q8W18_16720)	-	3228291..3228584 (-)	294	WP_106066158.1	late competence development ComFB family protein	-
Q8W18_RS16725 (Q8W18_16725)	comFA	3228651..3230030 (-)	1380	WP_306011283.1	DEAD/DEAH box helicase	Machinery gene
Q8W18_RS16730 (Q8W18_16730)	-	3230150..3230992 (-)	843	WP_058013557.1	DegV family protein	-
Q8W18_RS16735 (Q8W18_16735)	degU	3231210..3231899 (-)	690	WP_008348273.1	two-component system response regulator DegU	Regulator
Q8W18_RS16740 (Q8W18_16740)	degS	3231964..3233139 (-)	1176	WP_024719243.1	sensor histidine kinase	Regulator
Q8W18_RS16745 (Q8W18_16745)	-	3233361..3234029 (+)	669	WP_058013556.1	YigZ family protein	-
Q8W18_RS16750 (Q8W18_16750)	-	3234014..3235102 (+)	1089	WP_169055794.1	LCP family protein	-
Q8W18_RS16755 (Q8W18_16755)	-	3235138..3236205 (-)	1068	WP_169055795.1	glycosyltransferase family 4 protein	-
Q8W18_RS16760 (Q8W18_16760)	-	3236337..3237527 (-)	1191	WP_306012278.1	glycosyltransferase	-

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 45550.27 Da
• Isoelectric Point: 5.8757

>NTDB_id=867073 Q8W18_RS16740 WP_024719243.1 3231964..3233139(-) (degS) [Bacillus pumilus strain F12-21]
MTTPKMDPKLLDSIIMKMLSTVDGSKDEVFRIGEQSRQQYESLVEELKQIKQQVNEVIDFGDKLEVHTRHARNRLSEVSR
NFNKFSEEEIREAYEKAHNLQVELTMIQQREKQLRERRDDLERRLLSLQDVIERSETLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEEGFKEIRSLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEEYDGKTKITFQCLGDTENERIASQFEVALFRLAQEAVTNSLKHSEAEEISVKVEV
TKDFVTLIIKDDGKGFDMKDVKTNKNKSFGLLGMKERVDLLEGKMTIDSKIGLGTFIMIRVPLTLQNKIVK

Nucleotide

• Length: 1176 bp

>NTDB_id=867073 Q8W18_RS16740 WP_024719243.1 3231964..3233139(-) (degS) [Bacillus pumilus strain F12-21]
ATGACAACACCTAAAATGGATCCGAAATTATTGGATTCAATCATCATGAAAATGCTAAGTACAGTTGATGGCAGCAAGGA
CGAAGTATTTAGGATAGGCGAACAGTCCCGTCAACAATATGAAAGCCTTGTAGAAGAGCTGAAGCAAATCAAGCAGCAAG
TAAACGAAGTAATTGATTTTGGGGATAAACTAGAAGTCCATACGAGACATGCTAGAAATCGTTTATCTGAGGTCAGCAGA
AACTTCAACAAATTTAGCGAAGAAGAAATACGGGAGGCCTACGAAAAAGCACATAATCTGCAAGTGGAACTCACCATGAT
CCAGCAGCGCGAAAAGCAGCTGAGAGAAAGAAGAGACGATCTGGAAAGACGATTGTTAAGCCTGCAAGACGTCATTGAGC
GCTCTGAAACGCTTGTGAGCCAGATCACAGTGGTTCTCAACTATCTCAACCAGGACTTACGCCAAGTTGGCGTGTTACTT
GAAGATGCTCAAGCAAAACAAGATTTTGGACTTAGAATTATTGAAGCCCAAGAAGAAGAACGTAAAAGGGTATCCCGTGA
AATTCATGACGGTCCGGCACAGATGCTGGCAAACGTGATGATGCGCTCTGAATTAATTGAACGGATTTTCAGAGATCGTG
GGACAGAAGAAGGCTTTAAAGAAATTAGAAGTCTCAGACAGAATGTGCGAAATGCTCTGTACGAAGTGAGAAGAATCATT
TATGATTTAAGACCAATGGCTTTAGATGATTTGGGTCTCATTCCGACGCTAAGAAAATATTTAAACACAATCGAAGAGTA
TGATGGAAAAACCAAGATCACGTTCCAATGCCTAGGGGATACAGAAAATGAAAGAATTGCTTCTCAATTCGAAGTGGCAC
TGTTTAGACTAGCCCAAGAAGCTGTCACAAATTCACTGAAGCATTCCGAAGCTGAAGAAATCTCTGTAAAAGTAGAAGTG
ACGAAAGACTTTGTCACGTTAATTATCAAAGACGATGGAAAAGGTTTTGATATGAAAGATGTGAAAACAAATAAAAACAA
ATCTTTCGGTTTACTTGGCATGAAAGAACGCGTAGACTTACTGGAAGGTAAAATGACCATAGACTCAAAAATAGGTCTAG
GGACATTCATCATGATTCGCGTGCCATTAACATTACAAAATAAAATTGTAAAATAG

Domains

Predicted by InterproScan.

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A0A081LEM4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	85.455	98.465	0.841