Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7610_RS03995 Genome accession   NZ_CP131724
Coordinates   784870..786090 (+) Length   406 a.a.
NCBI ID   WP_005666687.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018N05-309     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 779870..791090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7610_RS03975 (Q7610_03975) corC 780836..781735 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  Q7610_RS03980 (Q7610_03980) ampD 782358..782918 (-) 561 WP_075985522.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  Q7610_RS03985 (Q7610_03985) pilA 783033..783482 (+) 450 WP_005666683.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  Q7610_RS03990 (Q7610_03990) pilB 783479..784873 (+) 1395 WP_005666685.1 GspE/PulE family protein Machinery gene
  Q7610_RS03995 (Q7610_03995) pilC 784870..786090 (+) 1221 WP_005666687.1 type II secretion system F family protein Machinery gene
  Q7610_RS04000 (Q7610_04000) pilD 786087..786779 (+) 693 WP_075985521.1 A24 family peptidase Machinery gene
  Q7610_RS04005 (Q7610_04005) rho 786834..788096 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  Q7610_RS04010 (Q7610_04010) metJ 788344..788661 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  Q7610_RS04015 (Q7610_04015) cueR 788675..789061 (-) 387 WP_038439225.1 Cu(I)-responsive transcriptional regulator -
  Q7610_RS04020 (Q7610_04020) - 789138..789344 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  Q7610_RS04025 (Q7610_04025) - 789430..789636 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46207.43 Da        Isoelectric Point: 9.8218

>NTDB_id=864837 Q7610_RS03995 WP_005666687.1 784870..786090(+) (pilC) [Haemophilus influenzae strain 2018N05-309]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMVYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQQKNQLISVTPIFGTIQKLSRLVNFSRSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=864837 Q7610_RS03995 WP_005666687.1 784870..786090(+) (pilC) [Haemophilus influenzae strain 2018N05-309]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCGCACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGGTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGTTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAACAGAAAAACCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCGCAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTTTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.973
  pilC Haemophilus influenzae Rd KW20

96.552

100

0.966
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379