Detailed information NTG0864498

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: Q7618_RS04540
• Genome accession: NZ_CP131715
• Coordinates: 888014..890254 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942408.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2006C08-243
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 883014..895254

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7618_RS04515 (Q7618_04510)	-	883406..883732 (+)	327	Protein_890	TfoX/Sxy family protein	-
Q7618_RS04520 (Q7618_04515)	ald	884033..885120 (-)	1088	Protein_891	alanine dehydrogenase	-
Q7618_RS04525 (Q7618_04520)	-	885154..886410 (-)	1257	WP_000530081.1	ISL3 family transposase	-
Q7618_RS04530 (Q7618_04525)	-	886743..887312 (+)	570	WP_000443772.1	GNAT family N-acetyltransferase	-
Q7618_RS04535 (Q7618_04530)	comEA/celA/cilE	887380..888030 (+)	651	WP_000387329.1	helix-hairpin-helix domain-containing protein	Machinery gene
Q7618_RS04540 (Q7618_04535)	comEC/celB	888014..890254 (+)	2241	WP_000942408.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
Q7618_RS04545 (Q7618_04540)	-	890433..890621 (+)	189	WP_001810030.1	hypothetical protein	-
Q7618_RS04550 (Q7618_04545)	-	890654..891241 (+)	588	WP_000939886.1	ABC transporter ATP-binding protein	-
Q7618_RS04555 (Q7618_04550)	-	891245..892429 (+)	1185	WP_000655949.1	ABC transporter permease	-
Q7618_RS04560 (Q7618_04555)	infC	892737..893267 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
Q7618_RS04565 (Q7618_04560)	rpmI	893300..893500 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
Q7618_RS04570 (Q7618_04565)	rplT	893552..893911 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
Q7618_RS04575 (Q7618_04570)	-	893969..894349 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84561.22 Da
• Isoelectric Point: 9.7561

>NTDB_id=864498 Q7618_RS04540 WP_000942408.1 888014..890254(+) (comEC/celB) [Streptococcus pneumoniae strain 2006C08-243]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGYLNTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=864498 Q7618_RS04540 WP_000942408.1 888014..890254(+) (comEC/celB) [Streptococcus pneumoniae strain 2006C08-243]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGTGAGTCAAAAT
TTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTTAACGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGATATCTGAACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGGAGACCGCTTGTCTTTGGTCAACCCAACGCATGGCTTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CACAGAGAAGCTTGATACCCTATCTTAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTATCAAAAGGCAGTTTGAAGCA
GAAGCAATTTGTGGTAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCCCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGCTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.855	100	0.979
comEC/celB	Streptococcus pneumoniae Rx1	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae D39	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae R6	96.783	100	0.968
comEC/celB	Streptococcus mitis SK321	92.225	100	0.922
comEC/celB	Streptococcus mitis NCTC 12261	91.946	99.866	0.918
comEC	Lactococcus lactis subsp. cremoris KW2	44.534	99.33	0.442