Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   Q7621_RS10235 Genome accession   NZ_CP131712
Coordinates   2037075..2037782 (+) Length   235 a.a.
NCBI ID   WP_000166475.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2008C09-280     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2032075..2042782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7621_RS10215 (Q7621_10210) argR 2033393..2033839 (-) 447 WP_001231472.1 arginine repressor -
  Q7621_RS10220 (Q7621_10215) argS 2033975..2035666 (+) 1692 WP_001092739.1 arginine--tRNA ligase -
  Q7621_RS10225 (Q7621_10220) - 2035981..2036508 (-) 528 Protein_1974 transposase family protein -
  Q7621_RS10230 (Q7621_10225) - 2036515..2036991 (+) 477 WP_000356602.1 cupin domain-containing protein -
  Q7621_RS10235 (Q7621_10230) vicR 2037075..2037782 (+) 708 WP_000166475.1 response regulator transcription factor Regulator
  Q7621_RS10240 (Q7621_10235) - 2037783..2039114 (+) 1332 WP_000833277.1 ATP-binding protein -
  Q7621_RS10245 (Q7621_10240) - 2039281..2040156 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  Q7621_RS10250 (Q7621_10245) pstC 2040274..2041137 (+) 864 WP_000595180.1 phosphate ABC transporter permease subunit PstC -
  Q7621_RS10255 (Q7621_10250) pstA 2041130..2041945 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  Q7621_RS10260 (Q7621_10255) pstB 2041947..2042699 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27230.61 Da        Isoelectric Point: 6.6568

>NTDB_id=864305 Q7621_RS10235 WP_000166475.1 2037075..2037782(+) (vicR) [Streptococcus pneumoniae strain 2008C09-280]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=864305 Q7621_RS10235 WP_000166475.1 2037075..2037782(+) (vicR) [Streptococcus pneumoniae strain 2008C09-280]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.773

99.149

0.404
  covR Streptococcus salivarius strain HSISS4

39.744

99.574

0.396