Detailed information NTG0864264

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: Q7621_RS04375
• Genome accession: NZ_CP131712
• Coordinates: 890089..891042 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 2008C09-280
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 885089..896042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7621_RS04350 (Q7621_04345)	rpmG	885832..885981 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
Q7621_RS04355 (Q7621_04350)	secG	886021..886254 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
Q7621_RS04360 (Q7621_04355)	rnr	886356..888710 (+)	2355	WP_000654898.1	ribonuclease R	-
Q7621_RS04365 (Q7621_04360)	smpB	888673..889140 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
Q7621_RS04370 (Q7621_04365)	tehB	889156..890016 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
Q7621_RS04375 (Q7621_04370)	coiA	890089..891042 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
Q7621_RS04380 (Q7621_04375)	pepF	891061..892863 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
Q7621_RS04385 (Q7621_04380)	-	892865..893578 (+)	714	WP_000230399.1	O-methyltransferase	-
Q7621_RS04390 (Q7621_04385)	prsA	893645..894586 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
Q7621_RS04395 (Q7621_04390)	-	894703..895044 (-)	342	Protein_866	IS3 family transposase	-
Q7621_RS04400 (Q7621_04395)	-	895458..895553 (+)	96	Protein_867	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=864264 Q7621_RS04375 WP_000495909.1 890089..891042(+) (coiA) [Streptococcus pneumoniae strain 2008C09-280]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=864264 Q7621_RS04375 WP_000495909.1 890089..891042(+) (coiA) [Streptococcus pneumoniae strain 2008C09-280]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435