Detailed information NTG0864196

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: Q7622_RS06485
• Genome accession: NZ_CP131711
• Coordinates: 1268801..1269754 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 2014C08-275
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1263801..1274754

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7622_RS06460 (Q7622_06455)	rpmG	1264544..1264693 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
Q7622_RS06465 (Q7622_06460)	secG	1264733..1264966 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
Q7622_RS06470 (Q7622_06465)	rnr	1265068..1267422 (+)	2355	WP_000654886.1	ribonuclease R	-
Q7622_RS06475 (Q7622_06470)	smpB	1267385..1267852 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
Q7622_RS06480 (Q7622_06475)	tehB	1267868..1268728 (+)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
Q7622_RS06485 (Q7622_06480)	coiA	1268801..1269754 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
Q7622_RS06490 (Q7622_06485)	pepF	1269773..1271584 (+)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
Q7622_RS06495 (Q7622_06490)	-	1271586..1272299 (+)	714	WP_000230400.1	O-methyltransferase	-
Q7622_RS06500 (Q7622_06495)	prsA	1272366..1273307 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
Q7622_RS06505 (Q7622_06500)	-	1273424..1273765 (-)	342	Protein_1286	IS3 family transposase	-
Q7622_RS06510 (Q7622_06505)	-	1274178..1274273 (+)	96	Protein_1287	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=864196 Q7622_RS06485 WP_000495909.1 1268801..1269754(+) (coiA) [Streptococcus pneumoniae strain 2014C08-275]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=864196 Q7622_RS06485 WP_000495909.1 1268801..1269754(+) (coiA) [Streptococcus pneumoniae strain 2014C08-275]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435