Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   Q7625_RS08690 Genome accession   NZ_CP131708
Coordinates   1725817..1726476 (+) Length   219 a.a.
NCBI ID   WP_000565006.1    Uniprot ID   A0A9P1LPI9
Organism   Streptococcus pneumoniae strain 2016C10-332     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1720817..1731476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7625_RS08665 (Q7625_08655) - 1721113..1721430 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  Q7625_RS08670 (Q7625_08660) - 1721445..1722341 (-) 897 WP_000825665.1 PEP phosphonomutase -
  Q7625_RS08675 (Q7625_08665) - 1722344..1723606 (-) 1263 WP_000413347.1 PTS transporter subunit EIIC -
  Q7625_RS08680 (Q7625_08670) - 1723886..1725064 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  Q7625_RS08685 (Q7625_08675) - 1725340..1725747 (-) 408 WP_000155434.1 GNAT family N-acetyltransferase -
  Q7625_RS08690 (Q7625_08680) cclA/cilC 1725817..1726476 (+) 660 WP_000565006.1 A24 family peptidase Machinery gene
  Q7625_RS08695 (Q7625_08685) - 1726528..1727679 (-) 1152 WP_000481756.1 XRE family transcriptional regulator -
  Q7625_RS08700 (Q7625_08690) - 1727694..1728425 (-) 732 WP_000934017.1 hypothetical protein -
  Q7625_RS08705 (Q7625_08695) - 1728654..1728755 (+) 102 Protein_1723 prepilin peptidase -
  Q7625_RS08710 (Q7625_08700) trpA 1728727..1729503 (-) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  Q7625_RS08715 (Q7625_08705) trpB 1729496..1730719 (-) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  Q7625_RS08720 (Q7625_08710) - 1730697..1731296 (-) 600 WP_000169888.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24860.02 Da        Isoelectric Point: 7.5762

>NTDB_id=863972 Q7625_RS08690 WP_000565006.1 1725817..1726476(+) (cclA/cilC) [Streptococcus pneumoniae strain 2016C10-332]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAALTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=863972 Q7625_RS08690 WP_000565006.1 1725817..1726476(+) (cclA/cilC) [Streptococcus pneumoniae strain 2016C10-332]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGCTTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTTCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae D39

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae R6

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae TIGR4

94.521

100

0.945
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872