Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   Q7626_RS10685 Genome accession   NZ_CP131707
Coordinates   2095316..2095978 (-) Length   220 a.a.
NCBI ID   WP_000649978.1    Uniprot ID   A0A0E8ARN2
Organism   Streptococcus pneumoniae strain 2018C08-270     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2090316..2100978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7626_RS10660 (Q7626_10635) - 2090467..2090733 (-) 267 WP_001278167.1 Veg family protein -
  Q7626_RS10665 (Q7626_10640) dnaB 2090735..2092087 (-) 1353 WP_000852486.1 replicative DNA helicase -
  Q7626_RS10670 (Q7626_10645) rplI 2092130..2092582 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  Q7626_RS10675 (Q7626_10650) - 2092579..2094552 (-) 1974 WP_000715110.1 DHH family phosphoesterase -
  Q7626_RS10680 (Q7626_10655) raiA 2094688..2095236 (-) 549 WP_000599104.1 ribosome-associated translation inhibitor RaiA -
  Q7626_RS10685 (Q7626_10660) comFC/cflB 2095316..2095978 (-) 663 WP_000649978.1 ComF family protein Machinery gene
  Q7626_RS10690 (Q7626_10665) comFA/cflA 2095975..2097273 (-) 1299 WP_000867612.1 DEAD/DEAH box helicase Machinery gene
  Q7626_RS10695 (Q7626_10670) - 2097329..2097964 (+) 636 WP_000395739.1 YigZ family protein -
  Q7626_RS10700 (Q7626_10675) cysK 2098249..2099169 (+) 921 WP_000029869.1 cysteine synthase A -
  Q7626_RS10705 (Q7626_10680) - 2099408..2099773 (-) 366 Protein_2070 IS66 family transposase -
  Q7626_RS10710 (Q7626_10685) - 2099755..2100042 (+) 288 Protein_2071 transposase -
  Q7626_RS10715 (Q7626_10690) tnpB 2100183..2100506 (-) 324 WP_000586643.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25240.11 Da        Isoelectric Point: 7.7116

>NTDB_id=863927 Q7626_RS10685 WP_000649978.1 2095316..2095978(-) (comFC/cflB) [Streptococcus pneumoniae strain 2018C08-270]
MKCLLCGQTMKTVLTFSSLLLLRNNDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=863927 Q7626_RS10685 WP_000649978.1 2095316..2095978(-) (comFC/cflB) [Streptococcus pneumoniae strain 2018C08-270]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATAATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E8ARN2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909