Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   Q7626_RS08425 Genome accession   NZ_CP131707
Coordinates   1677765..1678424 (+) Length   219 a.a.
NCBI ID   WP_061749563.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2018C08-270     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1672765..1683424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7626_RS08400 (Q7626_08390) - 1673070..1673387 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  Q7626_RS08405 (Q7626_08395) - 1673402..1674298 (-) 897 WP_000825663.1 PEP phosphonomutase -
  Q7626_RS08410 (Q7626_08400) - 1674301..1675563 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  Q7626_RS08415 (Q7626_08405) - 1675843..1677021 (+) 1179 WP_000175879.1 ROK family transcriptional regulator -
  Q7626_RS08420 (Q7626_08410) - 1677249..1677695 (-) 447 WP_000155425.1 GNAT family N-acetyltransferase -
  Q7626_RS08425 (Q7626_08415) cclA/cilC 1677765..1678424 (+) 660 WP_061749563.1 A24 family peptidase Machinery gene
  Q7626_RS08430 (Q7626_08420) - 1678476..1679627 (-) 1152 WP_000481747.1 XRE family transcriptional regulator -
  Q7626_RS08435 (Q7626_08425) - 1679642..1680373 (-) 732 WP_000934017.1 hypothetical protein -
  Q7626_RS08440 (Q7626_08430) - 1680602..1680703 (+) 102 Protein_1670 prepilin peptidase -
  Q7626_RS08445 (Q7626_08435) trpA 1680675..1681451 (-) 777 WP_001127048.1 tryptophan synthase subunit alpha -
  Q7626_RS08450 (Q7626_08440) trpB 1681444..1682667 (-) 1224 WP_000331287.1 tryptophan synthase subunit beta -
  Q7626_RS08455 (Q7626_08445) - 1682645..1683244 (-) 600 WP_000169909.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24848.00 Da        Isoelectric Point: 7.8950

>NTDB_id=863895 Q7626_RS08425 WP_061749563.1 1677765..1678424(+) (cclA/cilC) [Streptococcus pneumoniae strain 2018C08-270]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSKVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=863895 Q7626_RS08425 WP_061749563.1 1677765..1678424(+) (cclA/cilC) [Streptococcus pneumoniae strain 2018C08-270]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTAAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae D39

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae R6

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae TIGR4

94.521

100

0.945
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

85.845

100

0.858