Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   Q7627_RS10690 Genome accession   NZ_CP131706
Coordinates   2075825..2076487 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 2018N21-288     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2070825..2081487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7627_RS10665 (Q7627_10640) - 2070975..2071241 (-) 267 WP_001278167.1 Veg family protein -
  Q7627_RS10670 (Q7627_10645) dnaB 2071243..2072595 (-) 1353 WP_000852486.1 replicative DNA helicase -
  Q7627_RS10675 (Q7627_10650) rplI 2072639..2073091 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  Q7627_RS10680 (Q7627_10655) - 2073088..2075061 (-) 1974 WP_000715116.1 DHH family phosphoesterase -
  Q7627_RS10685 (Q7627_10660) raiA 2075197..2075745 (-) 549 WP_000599107.1 ribosome-associated translation inhibitor RaiA -
  Q7627_RS10690 (Q7627_10665) comFC/cflB 2075825..2076487 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  Q7627_RS10695 (Q7627_10670) comFA/cflA 2076484..2077782 (-) 1299 WP_000867610.1 DEAD/DEAH box helicase Machinery gene
  Q7627_RS10700 (Q7627_10675) - 2077838..2078473 (+) 636 WP_000395739.1 YigZ family protein -
  Q7627_RS10705 (Q7627_10680) cysK 2078758..2079678 (+) 921 WP_000029866.1 cysteine synthase A -
  Q7627_RS10710 (Q7627_10685) - 2079753..2080282 (-) 530 Protein_2071 transposase -
  Q7627_RS10715 (Q7627_10690) - 2080264..2080572 (+) 309 Protein_2072 transposase -
  Q7627_RS10720 (Q7627_10695) tnpB 2080713..2080928 (-) 216 WP_000376909.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=863850 Q7627_RS10690 WP_000649971.1 2075825..2076487(-) (comFC/cflB) [Streptococcus pneumoniae strain 2018N21-288]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=863850 Q7627_RS10690 WP_000649971.1 2075825..2076487(-) (comFC/cflB) [Streptococcus pneumoniae strain 2018N21-288]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914