Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   KI212_RS07485 Genome accession   NZ_AP024589
Coordinates   1554262..1554891 (-) Length   209 a.a.
NCBI ID   WP_059107800.1    Uniprot ID   -
Organism   Staphylococcus auricularis strain JCM 2421     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1549262..1559891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KI212_RS07455 (JCM2421_14880) - 1549648..1550886 (-) 1239 WP_059107806.1 aminopeptidase -
  KI212_RS07460 (JCM2421_14890) - 1550898..1551101 (-) 204 WP_059107805.1 DUF1128 domain-containing protein -
  KI212_RS07465 (JCM2421_14900) - 1551233..1551697 (+) 465 WP_059107804.1 low molecular weight protein-tyrosine-phosphatase -
  KI212_RS07470 (JCM2421_14910) - 1551703..1551987 (+) 285 WP_059107803.1 YtxH domain-containing protein -
  KI212_RS07475 (JCM2421_14920) - 1552312..1553487 (+) 1176 WP_059107802.1 YihY/virulence factor BrkB family protein -
  KI212_RS07480 (JCM2421_14930) - 1553603..1554181 (+) 579 WP_059107801.1 beta-class carbonic anhydrase -
  KI212_RS07485 (JCM2421_14940) vraR 1554262..1554891 (-) 630 WP_059107800.1 response regulator transcription factor Regulator
  KI212_RS07490 (JCM2421_14950) vraS 1554881..1555927 (-) 1047 WP_059107799.1 sensor histidine kinase Regulator
  KI212_RS07495 (JCM2421_14960) liaF 1555924..1556625 (-) 702 WP_059107798.1 cell wall-active antibiotics response protein LiaF -
  KI212_RS07500 (JCM2421_14970) - 1556643..1557029 (-) 387 WP_059107797.1 hypothetical protein -
  KI212_RS07505 (JCM2421_14980) map 1557188..1557943 (-) 756 WP_059107796.1 type I methionyl aminopeptidase -
  KI212_RS07510 (JCM2421_14990) - 1558187..1559173 (+) 987 WP_059107795.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23523.03 Da        Isoelectric Point: 4.8701

>NTDB_id=86230 KI212_RS07485 WP_059107800.1 1554262..1554891(-) (vraR) [Staphylococcus auricularis strain JCM 2421]
MPIKVLFVDDHEMVRIGISSYLSTQTDIEVVGEGESGKDAIAKAHELNPDLILMDLVMEDMDGVEATTQIKKDFPHIKVV
MLTSYIEDNEVYRALDAGVDSYILKTTSASGIADAIRKTHQGEAVFEPEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIN

Nucleotide


Download         Length: 630 bp        

>NTDB_id=86230 KI212_RS07485 WP_059107800.1 1554262..1554891(-) (vraR) [Staphylococcus auricularis strain JCM 2421]
ATGCCAATTAAAGTATTGTTTGTGGACGATCACGAGATGGTTAGGATCGGTATATCGAGCTATTTATCTACGCAAACAGA
TATTGAAGTTGTGGGTGAGGGCGAATCAGGCAAGGATGCGATTGCTAAAGCACATGAACTCAATCCCGACTTAATATTAA
TGGATCTTGTGATGGAAGATATGGATGGGGTAGAAGCGACAACACAAATTAAAAAAGACTTTCCGCATATTAAAGTCGTG
ATGCTGACAAGCTATATTGAAGACAATGAAGTTTATCGTGCGTTAGATGCAGGCGTAGATAGCTATATTTTAAAAACGAC
GAGTGCGAGCGGTATTGCTGACGCAATCCGTAAAACCCATCAAGGTGAAGCGGTATTTGAACCCGAAGTGTTAGTGAAAA
TGCGTAACCGTATGAAACAACGTGCGGAATTATATGAAATGTTGACCGAACGTGAAATGGAAATACTATTATTAATCGCA
AAAGGTTATTCTAACCAAGAAATTGCAAGTGCTTCCCATATTACGATTAAGACGGTTAAAACCCATGTAAGTAATATATT
AAGTAAGCTTGAGGTTCAAGACCGGACGCAAGCCGTCATCTACGCATTCCAACACAATTTAATTAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

34.081

100

0.364

Multiple sequence alignment