Detailed information NTG0860109

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V85_RS09955
• Genome accession: NZ_CP130544
• Coordinates: 2026980..2028023 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA06-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2021980..2033023

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V85_RS09925	-	2022398..2023654 (-)	1257	WP_001795438.1	aminopeptidase	-
Q3V85_RS09930	-	2023657..2023857 (-)	201	WP_000180461.1	DUF1128 family protein	-
Q3V85_RS09935	-	2024004..2024468 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V85_RS09940	-	2024475..2024750 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V85_RS09945	-	2025028..2026245 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q3V85_RS09950	vraR	2026361..2026990 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
Q3V85_RS09955	vraS	2026980..2028023 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V85_RS09960	liaF	2028020..2028721 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V85_RS09965	-	2028736..2029122 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V85_RS09970	map	2029339..2030097 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V85_RS09975	-	2030684..2031670 (+)	987	WP_262520319.1	aromatic acid exporter family protein	-
Q3V85_RS09980	-	2032101..2032514 (-)	414	WP_001549145.1	hypothetical protein	-
Q3V85_RS09985	-	2032543..2032654 (-)	112	Protein_1926	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=860109 Q3V85_RS09955 WP_001017131.1 2026980..2028023(-) (vraS) [Staphylococcus aureus strain SA06-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=860109 Q3V85_RS09955 WP_001017131.1 2026980..2028023(-) (vraS) [Staphylococcus aureus strain SA06-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1