Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   STYK_RS01870 Genome accession   NZ_AP024523
Coordinates   360083..360820 (+) Length   245 a.a.
NCBI ID   WP_261805131.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 355083..365820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS01835 (STYK_03290) - 355795..356448 (-) 654 WP_084887540.1 hypothetical protein -
  STYK_RS01840 (STYK_03300) - 356526..356807 (-) 282 WP_261805129.1 hypothetical protein -
  STYK_RS01845 (STYK_03310) - 356817..357227 (-) 411 WP_261056507.1 HIT family protein -
  STYK_RS01850 (STYK_03320) pptA 357295..358026 (+) 732 WP_261100319.1 ABC transporter ATP-binding protein Regulator
  STYK_RS01855 (STYK_03330) - 358023..359072 (+) 1050 WP_125447817.1 ABC transporter permease -
  STYK_RS01860 (STYK_03340) - 359135..359464 (-) 330 WP_261805130.1 helicase BlpT -
  STYK_RS01865 (STYK_03350) - 359740..360078 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  STYK_RS01870 (STYK_03360) comE/blpR 360083..360820 (+) 738 WP_261805131.1 response regulator transcription factor Regulator
  STYK_RS01875 (STYK_03370) - 360834..362174 (+) 1341 WP_001099893.1 sensor histidine kinase -
  STYK_RS01880 (STYK_03380) blpC 362218..362373 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  STYK_RS01885 (STYK_03390) - 362430..363791 (-) 1362 WP_001865175.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28794.95 Da        Isoelectric Point: 6.1013

>NTDB_id=85730 STYK_RS01870 WP_261805131.1 360083..360820(+) (comE/blpR) [Streptococcus toyakuensis strain TP1632]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCYRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=85730 STYK_RS01870 WP_261805131.1 360083..360820(+) (comE/blpR) [Streptococcus toyakuensis strain TP1632]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCTGAGTTCTTTTGAAGTTTTTGGTAAGCCAGATCAATTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCTATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.036

100

0.535
  comE/comE1 Streptococcus equinus JB1

42.616

96.735

0.412
  comE/comE2 Streptococcus equinus JB1

38.017

98.776

0.376

Multiple sequence alignment