Detailed information NTG0854821

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LLWG2_RS09040
• Genome accession: NZ_CP129660
• Coordinates: 1773506..1774777 (-)
• Length: 423 a.a.
• NCBI ID: WP_324187043.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain Wg2
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1772033..1772923	1773506..1774777	flank	583

Gene organization within MGE regions

Location: 1772033..1774777

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLWG2_RS09030 (LLWG2_09090)	-	1772033..1772923 (-)	891	WP_064305213.1	IS982 family transposase	-
LLWG2_RS09035 (LLWG2_09095)	comEC	1773000..1773509 (-)	510	WP_021165649.1	MBL fold metallo-hydrolase	Machinery gene
LLWG2_RS09040 (LLWG2_09100)	comEC	1773506..1774777 (-)	1272	WP_324187043.1	ComEC/Rec2 family competence protein	Machinery gene

Sequence

Protein

• Length: 423 a.a.
• Molecular weight: 49018.13 Da
• Isoelectric Point: 9.7194

>NTDB_id=854821 LLWG2_RS09040 WP_324187043.1 1773506..1774777(-) (comEC) [Lactococcus cremoris strain Wg2]
MIPILIVFAVFFLLINSLSIRDNENQPKNLSKIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKGFYQNLSQNC
QLSFTGNLEIPETQRNFNGFDDQKYLTSQNIYRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFG
FLSKDFNQMSDIYSSLGIIHLFALSGMQVNFFIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNI
RLTSLDNIAVTTLVLMLISPKFLLTTGGQLTLFYAFVISMLNHPFSNLNGLKKVLTESSVLSLCVLPLLIFDFHIFQPLS
ILLTIIFGFLFDFMLLPLLLCCFLISFLGFSLNLNYIFQILEWLVYKVDLPLHYPFVLGKPSSLELIILFVLIGLFVDSF
SHKKRRFFLIGFIFLFFSSLKIQ

Nucleotide

• Length: 1272 bp

>NTDB_id=854821 LLWG2_RS09040 WP_324187043.1 1773506..1774777(-) (comEC) [Lactococcus cremoris strain Wg2]
ATGATTCCGATATTAATTGTTTTTGCTGTATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACC
AAAAAATCTCTCAAAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGA
ATGGACAAAAATATCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAGGGTTTTATCAGAACTTAAGTCAAAATTGT
CAGTTAAGTTTCACAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAAC
TAGTCAAAATATCTATCGACAGATTACCATCCAACAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTT
TAAGGCGAAAGGCAATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACAGGTTTGCTTTTTGGC
TTTTTAAGTAAGGATTTTAATCAGATGAGCGATATTTACAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAAT
GCAAGTAAATTTTTTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTC
AAATTCCATTTTCTATTTTTTATGCTTTTATGACGGGATTATCGGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATT
CGTCTGACTTCTTTGGATAATATCGCAGTTACGACATTAGTTTTGATGCTCATAAGTCCAAAATTTTTACTGACGACTGG
TGGTCAGCTTACCTTGTTTTATGCTTTTGTCATTTCGATGCTTAATCATCCTTTTTCTAATTTAAATGGATTGAAAAAAG
TGCTGACAGAATCATCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTCCATATTTTTCAGCCTCTTTCA
ATATTATTAACAATTATATTTGGTTTTCTTTTTGATTTTATGTTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATT
TTTGGGATTTTCGCTCAATTTAAATTATATTTTTCAAATTCTAGAATGGCTAGTTTATAAAGTTGATTTACCCTTACATT
ACCCCTTTGTTTTGGGGAAACCTAGTTCACTCGAATTAATTATTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTT
TCTCATAAAAAAAGGAGATTTTTTTTAATTGGATTTATATTTTTATTTTTTTCATCACTAAAAATCCAATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (157-397)

• Domain of unknown function (DUF4131) (DUF4131) (56-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	97.122	98.582	0.957
comEC/celB	Streptococcus mitis SK321	46.512	91.489	0.426
comEC/celB	Streptococcus mitis NCTC 12261	45.995	91.489	0.421
comEC/celB	Streptococcus pneumoniae TIGR4	45.995	91.489	0.421
comEC/celB	Streptococcus pneumoniae Rx1	45.22	91.489	0.414
comEC/celB	Streptococcus pneumoniae D39	45.22	91.489	0.414
comEC/celB	Streptococcus pneumoniae R6	45.22	91.489	0.414